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Mixed Response to Cancer Immunotherapy is Driven by Intratumor Heterogeneity and Differential Interlesion Immune Infiltration.
Morinaga T, Inozume T, Kawazu M, Ueda Y, Sax N, Yamashita K, Kawashima S, Nagasaki J, Ueno T, Lin J, Ohara Y, Kuwata T, Yukami H, Kawazoe A, Shitara K, Honobe-Tabuchi A, Ohnuma T, Kawamura T, Umeda Y, Kawahara Y, Nakamura Y, Kiniwa Y, Morita A, Ichihara E, Kiura K, Enokida T, Tahara M, Hasegawa Y, Mano H, Suzuki Y, Nishikawa H, Togashi Y. Morinaga T, et al. Among authors: suzuki y. Cancer Res Commun. 2022 Jul 28;2(7):739-753. doi: 10.1158/2767-9764.CRC-22-0050. eCollection 2022 Jul. Cancer Res Commun. 2022. PMID: 36923281 Free PMC article.
Subclonal accumulation of immune escape mechanisms in microsatellite instability-high colorectal cancers.
Kobayashi Y, Niida A, Nagayama S, Saeki K, Haeno H, Takahashi KK, Hayashi S, Ozato Y, Saito H, Hasegawa T, Nakamura H, Tobo T, Kitagawa A, Sato K, Shimizu D, Hirata H, Hisamatsu Y, Toshima T, Yonemura Y, Masuda T, Mizuno S, Kawazu M, Kohsaka S, Ueno T, Mano H, Ishihara S, Uemura M, Mori M, Doki Y, Eguchi H, Oshima M, Suzuki Y, Shibata T, Mimori K. Kobayashi Y, et al. Among authors: suzuki y. Br J Cancer. 2023 Oct;129(7):1105-1118. doi: 10.1038/s41416-023-02395-8. Epub 2023 Aug 18. Br J Cancer. 2023. PMID: 37596408
Regulation of MEK inhibitor selumetinib sensitivity by AKT phosphorylation in the novel BRAF L525R mutant.
Nakai C, Mimaki S, Matsushima K, Shinozaki E, Yamazaki K, Muro K, Yamaguchi K, Nishina T, Yuki S, Shitara K, Bando H, Suzuki Y, Akagi K, Nomura S, Fujii S, Sugiyama M, Nishida N, Mizokami M, Koh Y, Koshizaka T, Okada H, Abe Y, Ohtsu A, Yoshino T, Tsuchihara K. Nakai C, et al. Among authors: suzuki y. Int J Clin Oncol. 2023 May;28(5):654-663. doi: 10.1007/s10147-023-02318-w. Epub 2023 Mar 1. Int J Clin Oncol. 2023. PMID: 36856908 Free PMC article.
Multiomics identifies the link between intratumor steatosis and the exhausted tumor immune microenvironment in hepatocellular carcinoma.
Murai H, Kodama T, Maesaka K, Tange S, Motooka D, Suzuki Y, Shigematsu Y, Inamura K, Mise Y, Saiura A, Ono Y, Takahashi Y, Kawasaki Y, Iino S, Kobayashi S, Idogawa M, Tokino T, Hashidate-Yoshida T, Shindou H, Miyazaki M, Imai Y, Tanaka S, Mita E, Ohkawa K, Hikita H, Sakamori R, Tatsumi T, Eguchi H, Morii E, Takehara T. Murai H, et al. Among authors: suzuki y. Hepatology. 2023 Jan 1;77(1):77-91. doi: 10.1002/hep.32573. Epub 2022 Jun 17. Hepatology. 2023. PMID: 35567547 Free PMC article.
Tumor heterogeneity and immune-evasive T follicular cell lymphoma phenotypes at single-cell resolution.
Suma S, Suehara Y, Fujisawa M, Abe Y, Hattori K, Makishima K, Sakamoto T, Sawa A, Bando H, Kaji D, Sugio T, Kato K, Akashi K, Matsue K, Carreras J, Nakamura N, Suzuki A, Suzuki Y, Ito K, Shiiba H, Chiba S, Sakata-Yanagimoto M. Suma S, et al. Among authors: suzuki y, suzuki a. Leukemia. 2024 Feb;38(2):340-350. doi: 10.1038/s41375-023-02093-7. Epub 2023 Nov 27. Leukemia. 2024. PMID: 38012392 Free PMC article.
Postoperative recurrence detection using individualized circulating tumor DNA in upper tract urothelial carcinoma.
Tamura D, Abe M, Hiraki H, Sasaki N, Yashima-Abo A, Ikarashi D, Kato R, Kato Y, Maekawa S, Kanehira M, Takata R, Maejima K, Sasagawa S, Fujita M, Suzuki Y, Nakagawa H, Iwaya T, Nishizuka SS, Obara W. Tamura D, et al. Among authors: suzuki y. Cancer Sci. 2024 Feb;115(2):529-539. doi: 10.1111/cas.16025. Epub 2023 Dec 11. Cancer Sci. 2024. PMID: 38083992 Free PMC article.
Convergent genomic diversity and novel BCAA metabolism in intrahepatic cholangiocarcinoma.
Kitagawa A, Osawa T, Noda M, Kobayashi Y, Aki S, Nakano Y, Saito T, Shimizu D, Komatsu H, Sugaya M, Takahashi J, Kosai K, Takao S, Motomura Y, Sato K, Hu Q, Fujii A, Wakiyama H, Tobo T, Uchida H, Sugimachi K, Shibata K, Utsunomiya T, Kobayashi S, Ishii H, Hasegawa T, Masuda T, Matsui Y, Niida A, Soga T, Suzuki Y, Miyano S, Aburatani H, Doki Y, Eguchi H, Mori M, Nakayama KI, Shimamura T, Shibata T, Mimori K. Kitagawa A, et al. Among authors: suzuki y. Br J Cancer. 2023 Jun;128(12):2206-2217. doi: 10.1038/s41416-023-02256-4. Epub 2023 Apr 19. Br J Cancer. 2023. PMID: 37076565 Free PMC article.
High N6-methyladenosine-activated TCEAL8 mRNA is a novel pancreatic cancer marker.
Hara T, Meng S, Sato H, Tatekawa S, Sasaki K, Takeda Y, Tsuji Y, Arao Y, Ofusa K, Kitagawa T, Yamada D, Takahashi H, Kobayashi S, Motooka D, Suzuki Y, Rennie S, Uchida S, Mori M, Ogawa K, Doki Y, Eguchi H, Ishii H. Hara T, et al. Among authors: suzuki y. Cancer Sci. 2024 Apr 24. doi: 10.1111/cas.16152. Online ahead of print. Cancer Sci. 2024. PMID: 38659235 Free article.
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