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Virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariants.
Tamura T, Ito J, Uriu K, Zahradnik J, Kida I, Anraku Y, Nasser H, Shofa M, Oda Y, Lytras S, Nao N, Itakura Y, Deguchi S, Suzuki R, Wang L, Begum MM, Kita S, Yajima H, Sasaki J, Sasaki-Tabata K, Shimizu R, Tsuda M, Kosugi Y, Fujita S, Pan L, Sauter D, Yoshimatsu K, Suzuki S, Asakura H, Nagashima M, Sadamasu K, Yoshimura K, Yamamoto Y, Nagamoto T, Schreiber G, Maenaka K; Genotype to Phenotype Japan (G2P-Japan) Consortium; Hashiguchi T, Ikeda T, Fukuhara T, Saito A, Tanaka S, Matsuno K, Takayama K, Sato K. Tamura T, et al. Among authors: suzuki s, suzuki r. Nat Commun. 2023 May 16;14(1):2800. doi: 10.1038/s41467-023-38435-3. Nat Commun. 2023. PMID: 37193706 Free PMC article.
Virological characteristics of the SARS-CoV-2 Omicron XBB.1.5 variant.
Tamura T, Irie T, Deguchi S, Yajima H, Tsuda M, Nasser H, Mizuma K, Plianchaisuk A, Suzuki S, Uriu K, Begum MM, Shimizu R, Jonathan M, Suzuki R, Kondo T, Ito H, Kamiyama A, Yoshimatsu K, Shofa M, Hashimoto R, Anraku Y, Kimura KT, Kita S, Sasaki J, Sasaki-Tabata K, Maenaka K, Nao N, Wang L, Oda Y; Genotype to Phenotype Japan (G2P-Japan) Consortium; Ikeda T, Saito A, Matsuno K, Ito J, Tanaka S, Sato K, Hashiguchi T, Takayama K, Fukuhara T. Tamura T, et al. Among authors: suzuki s, suzuki r. Nat Commun. 2024 Feb 8;15(1):1176. doi: 10.1038/s41467-024-45274-3. Nat Commun. 2024. PMID: 38332154 Free PMC article.
SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation.
Sanders DW, Jumper CC, Ackerman PJ, Bracha D, Donlic A, Kim H, Kenney D, Castello-Serrano I, Suzuki S, Tamura T, Tavares AH, Saeed M, Holehouse AS, Ploss A, Levental I, Douam F, Padera RF, Levy BD, Brangwynne CP. Sanders DW, et al. Among authors: suzuki s. Elife. 2021 Apr 23;10:e65962. doi: 10.7554/eLife.65962. Elife. 2021. PMID: 33890572 Free PMC article.
Low replicative fitness of neuraminidase inhibitor-resistant H7N9 avian influenza a virus with R292K substitution in neuraminidase in cynomolgus macaques compared with I222T substitution.
Suzuki S, Shichinohe S, Itoh Y, Nakayama M, Ishigaki H, Mori Y, Ogata-Nakahara A, Nguyen CT, Okamatsu M, Sakoda Y, Kida H, Ogasawara K. Suzuki S, et al. Antiviral Res. 2020 Jun;178:104790. doi: 10.1016/j.antiviral.2020.104790. Epub 2020 Apr 6. Antiviral Res. 2020. PMID: 32272175
Inactivated whole influenza virus particle vaccines induce neutralizing antibodies with an increase in immunoglobulin gene subclones of B-lymphocytes in cynomolgus macaques.
Shiohara M, Suzuki S, Shichinohe S, Ishigaki H, Nakayama M, Nomura N, Shingai M, Sekiya T, Ohno M, Iida S, Kawai N, Kawahara M, Yamagishi J, Ito K, Mitsumata R, Ikeda T, Motokawa K, Sobue T, Kida H, Ogasawara K, Itoh Y. Shiohara M, et al. Among authors: suzuki s. Vaccine. 2022 Jun 26;40(30):4026-4037. doi: 10.1016/j.vaccine.2022.05.045. Epub 2022 May 28. Vaccine. 2022. PMID: 35641357
Inactivated whole virus particle vaccine with potent immunogenicity and limited IL-6 induction is ideal for influenza.
Sekiya T, Mifsud EJ, Ohno M, Nomura N, Sasada M, Fujikura D, Daito T, Shingai M, Ohara Y, Nishimura T, Endo M, Mitsumata R, Ikeda T, Hatanaka H, Kitayama H, Motokawa K, Sobue T, Suzuki S, Itoh Y, Brown LE, Ogasawara K, Kino Y, Kida H. Sekiya T, et al. Among authors: suzuki s. Vaccine. 2019 Apr 3;37(15):2158-2166. doi: 10.1016/j.vaccine.2019.02.057. Epub 2019 Mar 8. Vaccine. 2019. PMID: 30857932
Immune profiling of influenza-specific B- and T-cell responses in macaques using flow cytometry-based assays.
Koutsakos M, Sekiya T, Chua BY, Nguyen THO, Wheatley AK, Juno JA, Ohno M, Nomura N, Ohara Y, Nishimura T, Endo M, Suzuki S, Ishigaki H, Nakayama M, Nguyen CT, Itoh Y, Shingai M, Ogasawara K, Kino Y, Kent SJ, Jackson DC, Brown LE, Kida H, Kedzierska K. Koutsakos M, et al. Among authors: suzuki s. Immunol Cell Biol. 2021 Jan;99(1):97-106. doi: 10.1111/imcb.12383. Epub 2020 Sep 7. Immunol Cell Biol. 2021. PMID: 32741011
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