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Senolysis by glutaminolysis inhibition ameliorates various age-associated disorders.
Johmura Y, Yamanaka T, Omori S, Wang TW, Sugiura Y, Matsumoto M, Suzuki N, Kumamoto S, Yamaguchi K, Hatakeyama S, Takami T, Yamaguchi R, Shimizu E, Ikeda K, Okahashi N, Mikawa R, Suematsu M, Arita M, Sugimoto M, Nakayama KI, Furukawa Y, Imoto S, Nakanishi M. Johmura Y, et al. Among authors: suzuki n. Science. 2021 Jan 15;371(6526):265-270. doi: 10.1126/science.abb5916. Science. 2021. PMID: 33446552
Fbxo22-mediated KDM4B degradation determines selective estrogen receptor modulator activity in breast cancer.
Johmura Y, Maeda I, Suzuki N, Wu W, Goda A, Morita M, Yamaguchi K, Yamamoto M, Nagasawa S, Kojima Y, Tsugawa K, Inoue N, Miyoshi Y, Osako T, Akiyama F, Maruyama R, Inoue JI, Furukawa Y, Ohta T, Nakanishi M. Johmura Y, et al. Among authors: suzuki n. J Clin Invest. 2018 Dec 3;128(12):5603-5619. doi: 10.1172/JCI121679. Epub 2018 Nov 12. J Clin Invest. 2018. PMID: 30418174 Free PMC article.
TP53/p53-FBXO22-TFEB controls basal autophagy to govern hormesis.
Suzuki N, Johmura Y, Wang TW, Migita T, Wu W, Noguchi R, Yamaguchi K, Furukawa Y, Nakamura S, Miyoshi I, Yoshimori T, Ohta T, Nakanishi M. Suzuki N, et al. Autophagy. 2021 Nov;17(11):3776-3793. doi: 10.1080/15548627.2021.1897961. Epub 2021 Mar 11. Autophagy. 2021. PMID: 33706682 Free PMC article.
Blocking PD-L1-PD-1 improves senescence surveillance and ageing phenotypes.
Wang TW, Johmura Y, Suzuki N, Omori S, Migita T, Yamaguchi K, Hatakeyama S, Yamazaki S, Shimizu E, Imoto S, Furukawa Y, Yoshimura A, Nakanishi M. Wang TW, et al. Among authors: suzuki n. Nature. 2022 Nov;611(7935):358-364. doi: 10.1038/s41586-022-05388-4. Epub 2022 Nov 2. Nature. 2022. PMID: 36323784
LONRF2 is a protein quality control ubiquitin ligase whose deficiency causes late-onset neurological deficits.
Li D, Johmura Y, Morimoto S, Doi M, Nakanishi K, Ozawa M, Tsunekawa Y, Inoue-Yamauchi A, Naruse H, Matsukawa T, Takeshita Y, Suzuki N, Aoki M, Nishiyama A, Zeng X, Konishi C, Suzuki N, Nishiyama A, Harris AS, Morita M, Yamaguchi K, Furukawa Y, Nakai K, Tsuji S, Yamazaki S, Yamanashi Y, Shimada S, Okada T, Okano H, Toda T, Nakanishi M. Li D, et al. Among authors: suzuki n. Nat Aging. 2023 Aug;3(8):1001-1019. doi: 10.1038/s43587-023-00464-4. Epub 2023 Jul 20. Nat Aging. 2023. PMID: 37474791
An aspirin-free strategy and optical coherence tomography observations after percutaneous coronary intervention: Insights from the STOPDAPT-3 trial.
Obayashi Y, Natsuaki M, Watanabe H, Morimoto T, Yamamoto K, Nishikawa R, Miyazawa A, Suzuki N, Suwa S, Kirigaya H, Wakabayashi K, Kawai K, Onishi Y, Morishima I, Okayama H, Uehara H, Hibi K, Ono K, Kimura T; STOPDAPT-3 Investigators. Obayashi Y, et al. Among authors: suzuki n. J Cardiol. 2024 May 10:S0914-5087(24)00083-2. doi: 10.1016/j.jjcc.2024.05.002. Online ahead of print. J Cardiol. 2024. PMID: 38735384 No abstract available.
6,020 results