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Dual Glycolate Oxidase/Lactate Dehydrogenase A Inhibitors for Primary Hyperoxaluria.
ACS Med Chem Lett. 2021 May 20;12(7):1116-1123. doi: 10.1021/acsmedchemlett.1c00196. eCollection 2021 Jul 8.
ACS Med Chem Lett. 2021.
PMID: 34267881
Free PMC article.
Development of Novel Monoamine Oxidase-B (MAO-B) Inhibitors with Reduced Blood-Brain Barrier Permeability for the Potential Management of Noncentral Nervous System (CNS) Diseases.
Gealageas R, Devineau A, So PPL, Kim CMJ, Surendradoss J, Buchwalder C, Heller M, Goebeler V, Dullaghan EM, Grierson DS, Putnins EE.
Gealageas R, et al. Among authors: surendradoss j.
J Med Chem. 2018 Aug 23;61(16):7043-7064. doi: 10.1021/acs.jmedchem.7b01588. Epub 2018 Aug 1.
J Med Chem. 2018.
PMID: 30016860
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Assessment of the role of in situ generated (E)-2,4-diene-valproic acid in the toxicity of valproic acid and (E)-2-ene-valproic acid in sandwich-cultured rat hepatocytes.
Surendradoss J, Chang TK, Abbott FS.
Surendradoss J, et al.
Toxicol Appl Pharmacol. 2012 Nov 1;264(3):413-22. doi: 10.1016/j.taap.2012.08.018. Epub 2012 Aug 25.
Toxicol Appl Pharmacol. 2012.
PMID: 22940460
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Glutathione depletion by valproic acid in sandwich-cultured rat hepatocytes: Role of biotransformation and temporal relationship with onset of toxicity.
Kiang TK, Teng XW, Surendradoss J, Karagiozov S, Abbott FS, Chang TK.
Kiang TK, et al. Among authors: surendradoss j.
Toxicol Appl Pharmacol. 2011 May 1;252(3):318-24. doi: 10.1016/j.taap.2011.03.004. Epub 2011 Mar 22.
Toxicol Appl Pharmacol. 2011.
PMID: 21397622
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Evaluation of in situ generated valproyl 1-O-β-acyl glucuronide in valproic acid toxicity in sandwich-cultured rat hepatocytes.
Surendradoss J, Chang TK, Abbott FS.
Surendradoss J, et al.
Drug Metab Dispos. 2014 Nov;42(11):1834-42. doi: 10.1124/dmd.114.059352. Epub 2014 Aug 21.
Drug Metab Dispos. 2014.
PMID: 25147275
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A rapid and sensitive assay to quantify valproyl 1-O-acyl glucuronide in supernatants of sandwich-cultured rat hepatocytes using ultra-high performance liquid chromatography-tandem mass spectrometry.
Surendradoss J, Szeitz A, Teng XW, Chang TK, Abbott FS.
Surendradoss J, et al.
J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Aug 1;932:40-9. doi: 10.1016/j.jchromb.2013.06.006. Epub 2013 Jun 13.
J Chromatogr B Analyt Technol Biomed Life Sci. 2013.
PMID: 23827518
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Role of oxidative metabolism in the effect of valproic acid on markers of cell viability, necrosis, and oxidative stress in sandwich-cultured rat hepatocytes.
Kiang TK, Teng XW, Karagiozov S, Surendradoss J, Chang TK, Abbott FS.
Kiang TK, et al. Among authors: surendradoss j.
Toxicol Sci. 2010 Dec;118(2):501-9. doi: 10.1093/toxsci/kfq294. Epub 2010 Sep 22.
Toxicol Sci. 2010.
PMID: 20861068
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