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TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7-9.
Heinz LX, Lee J, Kapoor U, Kartnig F, Sedlyarov V, Papakostas K, César-Razquin A, Essletzbichler P, Goldmann U, Stefanovic A, Bigenzahn JW, Scorzoni S, Pizzagalli MD, Bensimon A, Müller AC, King FJ, Li J, Girardi E, Mbow ML, Whitehurst CE, Rebsamen M, Superti-Furga G. Heinz LX, et al. Nature. 2020 May;581(7808):316-322. doi: 10.1038/s41586-020-2282-0. Epub 2020 May 13. Nature. 2020. PMID: 32433612 Free PMC article.
IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNA.
Pichlmair A, Lassnig C, Eberle CA, Górna MW, Baumann CL, Burkard TR, Bürckstümmer T, Stefanovic A, Krieger S, Bennett KL, Rülicke T, Weber F, Colinge J, Müller M, Superti-Furga G. Pichlmair A, et al. Nat Immunol. 2011 Jun 5;12(7):624-30. doi: 10.1038/ni.2048. Nat Immunol. 2011. PMID: 21642987
Complement factor H binds malondialdehyde epitopes and protects from oxidative stress.
Weismann D, Hartvigsen K, Lauer N, Bennett KL, Scholl HP, Charbel Issa P, Cano M, Brandstätter H, Tsimikas S, Skerka C, Superti-Furga G, Handa JT, Zipfel PF, Witztum JL, Binder CJ. Weismann D, et al. Nature. 2011 Oct 5;478(7367):76-81. doi: 10.1038/nature10449. Nature. 2011. PMID: 21979047 Free PMC article.
Viral immune modulators perturb the human molecular network by common and unique strategies.
Pichlmair A, Kandasamy K, Alvisi G, Mulhern O, Sacco R, Habjan M, Binder M, Stefanovic A, Eberle CA, Goncalves A, Bürckstümmer T, Müller AC, Fauster A, Holze C, Lindsten K, Goodbourn S, Kochs G, Weber F, Bartenschlager R, Bowie AG, Bennett KL, Colinge J, Superti-Furga G. Pichlmair A, et al. Nature. 2012 Jul 26;487(7408):486-90. doi: 10.1038/nature11289. Nature. 2012. PMID: 22810585
Systems-pharmacology dissection of a drug synergy in imatinib-resistant CML.
Winter GE, Rix U, Carlson SM, Gleixner KV, Grebien F, Gridling M, Müller AC, Breitwieser FP, Bilban M, Colinge J, Valent P, Bennett KL, White FM, Superti-Furga G. Winter GE, et al. Nat Chem Biol. 2012 Nov;8(11):905-912. doi: 10.1038/nchembio.1085. Epub 2012 Sep 30. Nat Chem Biol. 2012. PMID: 23023260 Free PMC article.
Protein interaction networks in innate immunity.
Rebsamen M, Kandasamy RK, Superti-Furga G. Rebsamen M, et al. Trends Immunol. 2013 Dec;34(12):610-9. doi: 10.1016/j.it.2013.05.002. Epub 2013 Jul 2. Trends Immunol. 2013. PMID: 23827258 Review.
279 results