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A novel pentamethoxyflavone down-regulates tumor cell survival and proliferative and angiogenic gene products through inhibition of IκB kinase activation and sensitizes tumor cells to apoptosis by cytokines and chemotherapeutic agents.
Phromnoi K, Reuter S, Sung B, Prasad S, Kannappan R, Yadav VR, Chanmahasathien W, Limtrakul P, Aggarwal BB. Phromnoi K, et al. Among authors: sung b. Mol Pharmacol. 2011 Feb;79(2):279-89. doi: 10.1124/mol.110.067512. Epub 2010 Oct 7. Mol Pharmacol. 2011. PMID: 20930110 Free PMC article. Retracted.
Thiocolchicoside exhibits anticancer effects through downregulation of NF-κB pathway and its regulated gene products linked to inflammation and cancer.
Reuter S, Prasad S, Phromnoi K, Ravindran J, Sung B, Yadav VR, Kannappan R, Chaturvedi MM, Aggarwal BB. Reuter S, et al. Among authors: sung b. Cancer Prev Res (Phila). 2010 Nov;3(11):1462-72. doi: 10.1158/1940-6207.CAPR-10-0037. Epub 2010 Oct 26. Cancer Prev Res (Phila). 2010. PMID: 20978115 Free PMC article.
Ursolic acid inhibits growth and metastasis of human colorectal cancer in an orthotopic nude mouse model by targeting multiple cell signaling pathways: chemosensitization with capecitabine.
Prasad S, Yadav VR, Sung B, Reuter S, Kannappan R, Deorukhkar A, Diagaradjane P, Wei C, Baladandayuthapani V, Krishnan S, Guha S, Aggarwal BB. Prasad S, et al. Among authors: sung b. Clin Cancer Res. 2012 Sep 15;18(18):4942-53. doi: 10.1158/1078-0432.CCR-11-2805. Epub 2012 Jul 25. Clin Cancer Res. 2012. PMID: 22832932 Free PMC article.
553 results