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Integrative discovery of treatments for high-risk neuroblastoma.
Almstedt E, Elgendy R, Hekmati N, Rosén E, Wärn C, Olsen TK, Dyberg C, Doroszko M, Larsson I, Sundström A, Arsenian Henriksson M, Påhlman S, Bexell D, Vanlandewijck M, Kogner P, Jörnsten R, Krona C, Nelander S. Almstedt E, et al. Among authors: sundstrom a. Nat Commun. 2020 Jan 3;11(1):71. doi: 10.1038/s41467-019-13817-8. Nat Commun. 2020. PMID: 31900415 Free PMC article.
Deep immune profiling reveals targetable mechanisms of immune evasion in immune checkpoint inhibitor-refractory glioblastoma.
Simonds EF, Lu ED, Badillo O, Karimi S, Liu EV, Tamaki W, Rancan C, Downey KM, Stultz J, Sinha M, McHenry LK, Nasholm NM, Chuntova P, Sundström A, Genoud V, Shahani SA, Wang LD, Brown CE, Walker PR, Swartling FJ, Fong L, Okada H, Weiss WA, Hellström M. Simonds EF, et al. Among authors: sundstrom a. J Immunother Cancer. 2021 Jun;9(6):e002181. doi: 10.1136/jitc-2020-002181. J Immunother Cancer. 2021. PMID: 34083417 Free PMC article.
Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma.
Borgenvik A, Holmberg KO, Bolin S, Zhao M, Savov V, Rosén G, Hutter S, Garancher A, Rahmanto AS, Bergström T, Olsen TK, Mainwaring OJ, Sattanino D, Verbaan AD, Rusert JM, Sundström A, Bravo MB, Dang Y, Wenz AS, Richardson S, Fotaki G, Hill RM, Dubuc AM, Kalushkova A, Remke M, Čančer M, Jernberg-Wiklund H, Giraud G, Chen X, Taylor MD, Sangfelt O, Clifford SC, Schüller U, Wechsler-Reya RJ, Weishaupt H, Swartling FJ. Borgenvik A, et al. Among authors: sundstrom a. Cancer Res. 2022 Dec 16;82(24):4586-4603. doi: 10.1158/0008-5472.CAN-22-2108. Cancer Res. 2022. PMID: 36219398 Free PMC article.
Combined BET bromodomain and CDK2 inhibition in MYC-driven medulloblastoma.
Bolin S, Borgenvik A, Persson CU, Sundström A, Qi J, Bradner JE, Weiss WA, Cho YJ, Weishaupt H, Swartling FJ. Bolin S, et al. Among authors: sundstrom a. Oncogene. 2018 May;37(21):2850-2862. doi: 10.1038/s41388-018-0135-1. Epub 2018 Mar 7. Oncogene. 2018. PMID: 29511348 Free PMC article.
Modeling SHH-driven medulloblastoma with patient iPS cell-derived neural stem cells.
Susanto E, Marin Navarro A, Zhou L, Sundström A, van Bree N, Stantic M, Moslem M, Tailor J, Rietdijk J, Zubillaga V, Hübner JM, Weishaupt H, Wolfsberger J, Alafuzoff I, Nordgren A, Magnaldo T, Siesjö P, Johnsen JI, Kool M, Tammimies K, Darabi A, Swartling FJ, Falk A, Wilhelm M. Susanto E, et al. Among authors: sundstrom a. Proc Natl Acad Sci U S A. 2020 Aug 18;117(33):20127-20138. doi: 10.1073/pnas.1920521117. Epub 2020 Aug 3. Proc Natl Acad Sci U S A. 2020. PMID: 32747535 Free PMC article.
FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma.
Suryo Rahmanto A, Savov V, Brunner A, Bolin S, Weishaupt H, Malyukova A, Rosén G, Čančer M, Hutter S, Sundström A, Kawauchi D, Jones DT, Spruck C, Taylor MD, Cho YJ, Pfister SM, Kool M, Korshunov A, Swartling FJ, Sangfelt O. Suryo Rahmanto A, et al. Among authors: sundstrom a. EMBO J. 2016 Oct 17;35(20):2192-2212. doi: 10.15252/embj.201693889. Epub 2016 Sep 13. EMBO J. 2016. PMID: 27625374 Free PMC article.
179 results