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Mechanism of high-mannose N-glycan breakdown and metabolism by Bifidobacterium longum.
Cordeiro RL, Santos CR, Domingues MN, Lima TB, Pirolla RAS, Morais MAB, Colombari FM, Miyamoto RY, Persinoti GF, Borges AC, de Farias MA, Stoffel F, Li C, Gozzo FC, van Heel M, Guerin ME, Sundberg EJ, Wang LX, Portugal RV, Giuseppe PO, Murakami MT. Cordeiro RL, et al. Among authors: sundberg ej. Nat Chem Biol. 2023 Feb;19(2):218-229. doi: 10.1038/s41589-022-01202-4. Epub 2022 Nov 28. Nat Chem Biol. 2023. PMID: 36443572 Free PMC article.
Molecular Basis of Broad Spectrum N-Glycan Specificity and Processing of Therapeutic IgG Monoclonal Antibodies by Endoglycosidase S2.
Klontz EH, Trastoy B, Deredge D, Fields JK, Li C, Orwenyo J, Marina A, Beadenkopf R, Günther S, Flores J, Wintrode PL, Wang LX, Guerin ME, Sundberg EJ. Klontz EH, et al. Among authors: sundberg ej. ACS Cent Sci. 2019 Mar 27;5(3):524-538. doi: 10.1021/acscentsci.8b00917. Epub 2019 Feb 6. ACS Cent Sci. 2019. PMID: 30937380 Free PMC article.
Sculpting therapeutic monoclonal antibody N-glycans using endoglycosidases.
Trastoy B, Du JJ, García-Alija M, Li C, Klontz EH, Wang LX, Sundberg EJ, Guerin ME. Trastoy B, et al. Among authors: sundberg ej. Curr Opin Struct Biol. 2022 Feb;72:248-259. doi: 10.1016/j.sbi.2021.11.016. Epub 2022 Jan 5. Curr Opin Struct Biol. 2022. PMID: 34998123 Free PMC article. Review.
Mechanism of cooperative N-glycan processing by the multi-modular endoglycosidase EndoE.
García-Alija M, Du JJ, Ordóñez I, Diz-Vallenilla A, Moraleda-Montoya A, Sultana N, Huynh CG, Li C, Donahue TC, Wang LX, Trastoy B, Sundberg EJ, Guerin ME. García-Alija M, et al. Among authors: sundberg ej. Nat Commun. 2022 Mar 3;13(1):1137. doi: 10.1038/s41467-022-28722-w. Nat Commun. 2022. PMID: 35241669 Free PMC article.
Mechanism of antibody-specific deglycosylation and immune evasion by Streptococcal IgG-specific endoglycosidases.
Trastoy B, Du JJ, Cifuente JO, Rudolph L, García-Alija M, Klontz EH, Deredge D, Sultana N, Huynh CG, Flowers MW, Li C, Sastre DE, Wang LX, Corzana F, Mallagaray A, Sundberg EJ, Guerin ME. Trastoy B, et al. Among authors: sundberg ej. Nat Commun. 2023 Mar 27;14(1):1705. doi: 10.1038/s41467-023-37215-3. Nat Commun. 2023. PMID: 36973249 Free PMC article.
116 results