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A novel multivalent, single-domain antibody targeting TcdA and TcdB prevents fulminant Clostridium difficile infection in mice.
Yang Z, Schmidt D, Liu W, Li S, Shi L, Sheng J, Chen K, Yu H, Tremblay JM, Chen X, Piepenbrink KH, Sundberg EJ, Kelly CP, Bai G, Shoemaker CB, Feng H. Yang Z, et al. Among authors: sundberg ej. J Infect Dis. 2014 Sep 15;210(6):964-72. doi: 10.1093/infdis/jiu196. Epub 2014 Mar 27. J Infect Dis. 2014. PMID: 24683195 Free PMC article.
Some of the most interesting CASP11 targets through the eyes of their authors.
Kryshtafovych A, Moult J, Baslé A, Burgin A, Craig TK, Edwards RA, Fass D, Hartmann MD, Korycinski M, Lewis RJ, Lorimer D, Lupas AN, Newman J, Peat TS, Piepenbrink KH, Prahlad J, van Raaij MJ, Rohwer F, Segall AM, Seguritan V, Sundberg EJ, Singh AK, Wilson MA, Schwede T. Kryshtafovych A, et al. Among authors: sundberg ej. Proteins. 2016 Sep;84 Suppl 1(Suppl Suppl 1):34-50. doi: 10.1002/prot.24942. Epub 2015 Nov 16. Proteins. 2016. PMID: 26473983 Free PMC article.
The NEU1-selective sialidase inhibitor, C9-butyl-amide-DANA, blocks sialidase activity and NEU1-mediated bioactivities in human lung in vitro and murine lung in vivo.
Hyun SW, Liu A, Liu Z, Cross AS, Verceles AC, Magesh S, Kommagalla Y, Kona C, Ando H, Luzina IG, Atamas SP, Piepenbrink KH, Sundberg EJ, Guang W, Ishida H, Lillehoj EP, Goldblum SE. Hyun SW, et al. Among authors: sundberg ej. Glycobiology. 2016 Aug;26(8):834-49. doi: 10.1093/glycob/cww060. Epub 2016 May 25. Glycobiology. 2016. PMID: 27226251 Free PMC article.
Type IV pili promote early biofilm formation by Clostridium difficile.
Maldarelli GA, Piepenbrink KH, Scott AJ, Freiberg JA, Song Y, Achermann Y, Ernst RK, Shirtliff ME, Sundberg EJ, Donnenberg MS, von Rosenvinge EC. Maldarelli GA, et al. Among authors: sundberg ej. Pathog Dis. 2016 Aug;74(6):ftw061. doi: 10.1093/femspd/ftw061. Epub 2016 Jun 30. Pathog Dis. 2016. PMID: 27369898 Free PMC article.
Structural Diversity in the Type IV Pili of Multidrug-resistant Acinetobacter.
Piepenbrink KH, Lillehoj E, Harding CM, Labonte JW, Zuo X, Rapp CA, Munson RS Jr, Goldblum SE, Feldman MF, Gray JJ, Sundberg EJ. Piepenbrink KH, et al. Among authors: sundberg ej. J Biol Chem. 2016 Oct 28;291(44):22924-22935. doi: 10.1074/jbc.M116.751099. Epub 2016 Sep 15. J Biol Chem. 2016. PMID: 27634041 Free PMC article.
125 results