Sun Y - Search Results

1

Discovery of 7H-Pyrrolo[2,3-d]pyrimidine Derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors.

Wu F, Li H, An Q, Sun Y, Yu J, Cao W, Sun P, Diao X, Meng L, Xu S. Wu F, et al. Among authors: sun p, sun y. Eur J Med Chem. 2023 Jun 5;254:115355. doi: 10.1016/j.ejmech.2023.115355. Epub 2023 Apr 10. Eur J Med Chem. 2023. PMID: 37062169

2

Discovery of a potent, selective, and covalent ZAP-70 kinase inhibitor.

Rao D, Li H, Ren X, Sun Y, Wen C, Zheng M, Huang H, Tang W, Xu S. Rao D, et al. Among authors: sun y. Eur J Med Chem. 2021 Jul 5;219:113393. doi: 10.1016/j.ejmech.2021.113393. Epub 2021 Mar 30. Eur J Med Chem. 2021. PMID: 33845236

3

Structure-Based Discovery of a Series of NSD2-PWWP1 Inhibitors.

Li N, Yang H, Liu K, Zhou L, Huang Y, Cao D, Li Y, Sun Y, Yu A, Du Z, Yu F, Zhang Y, Wang B, Geng M, Li J, Xiong B, Xu S, Huang X, Liu T. Li N, et al. Among authors: sun y. J Med Chem. 2022 Jul 14;65(13):9459-9477. doi: 10.1021/acs.jmedchem.2c00709. Epub 2022 Jun 15. J Med Chem. 2022. PMID: 35704853

4

Discovery of a potent and selective proteolysis targeting chimera (PROTAC) degrader of NSD3 histone methyltransferase.

Sun Y, Zhang Y, Chen X, Yu A, Du W, Huang Y, Wu F, Yu L, Li J, Wen C, Yang H, Shi Q, Geng M, Huang X, Xu S. Sun Y, et al. Eur J Med Chem. 2022 Sep 5;239:114528. doi: 10.1016/j.ejmech.2022.114528. Epub 2022 Jun 13. Eur J Med Chem. 2022. PMID: 35717870

5

Development of a potent benzonitrile-based inhibitor of glutaminyl-peptide cyclotransferase-like protein (QPCTL) with antitumor efficacy.

Yu L, Zhao P, Sun Y, Zheng Z, Du W, Zhang L, Li Y, Xie L, Xu S, Wang P. Yu L, et al. Among authors: sun y. Signal Transduct Target Ther. 2023 Dec 15;8(1):454. doi: 10.1038/s41392-023-01715-x. Signal Transduct Target Ther. 2023. PMID: 38097557 Free PMC article. No abstract available.

6

Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor.

Sun Y, Chen Z, Liu G, Chen X, Shi Z, Feng H, Yu L, Li G, Ding K, Huang H, Zhang Z, Xu S. Sun Y, et al. Bioorg Chem. 2024 Feb;143:107053. doi: 10.1016/j.bioorg.2023.107053. Epub 2023 Dec 25. Bioorg Chem. 2024. PMID: 38159497

7

Discovery of a PROTAC degrader for METTL3-METTL14 complex.

Du W, Huang Y, Chen X, Deng Y, Sun Y, Yang H, Shi Q, Wu F, Liu G, Huang H, Ding J, Huang X, Xu S. Du W, et al. Among authors: sun y. Cell Chem Biol. 2024 Jan 18;31(1):177-183.e17. doi: 10.1016/j.chembiol.2023.12.009. Epub 2024 Jan 8. Cell Chem Biol. 2024. PMID: 38194973

8

Discovery of Pyrido[2,3-d]pyrimidin-7-one Derivatives as Highly Potent and Efficacious Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 (ENPP1) Inhibitors for Cancer Treatment.

Sun Y, Chen M, Han Y, Li W, Ma X, Shi Z, Zhou Y, Xu L, Yu L, Wang Y, Yu J, Diao X, Meng L, Xu S. Sun Y, et al. J Med Chem. 2024 Mar 14;67(5):3986-4006. doi: 10.1021/acs.jmedchem.3c02288. Epub 2024 Feb 22. J Med Chem. 2024. PMID: 38387074

9

Chiral phosphine-catalyzed tunable cycloaddition reactions of allenoates with benzofuranone-derived olefins for a highly regio-, diastereo- and enantioselective synthesis of spiro-benzofuranones.

Wang D, Wang GP, Sun YL, Zhu SF, Wei Y, Zhou QL, Shi M. Wang D, et al. Among authors: sun yl. Chem Sci. 2015 Dec 1;6(12):7319-7325. doi: 10.1039/c5sc03135d. Epub 2015 Sep 15. Chem Sci. 2015. PMID: 29861963 Free PMC article.

10

Epidemiological and etiological investigations of hand, foot, and mouth disease in Jiashan, northeastern Zhejiang Province, China, during 2016 to 2022.

Yuan Y, Chen Y, Huang J, Bao X, Shen W, Sun Y, Mao H. Yuan Y, et al. Among authors: sun y. Front Public Health. 2024 May 1;12:1377861. doi: 10.3389/fpubh.2024.1377861. eCollection 2024. Front Public Health. 2024. PMID: 38751577 Free PMC article.

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