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Loss of SIRT5 promotes bile acid-induced immunosuppressive microenvironment and hepatocarcinogenesis.
Sun R, Zhang Z, Bao R, Guo X, Gu Y, Yang W, Wei J, Chen X, Tong L, Meng J, Zhong C, Zhang C, Zhang J, Sun Y, Ling C, Tong X, Yu FX, Yu H, Qu W, Zhao B, Guo W, Qian M, Saiyin H, Liu Y, Liu RH, Xie C, Liu W, Xiong Y, Guan KL, Shi Y, Wang P, Ye D. Sun R, et al. Among authors: sun y. J Hepatol. 2022 Aug;77(2):453-466. doi: 10.1016/j.jhep.2022.02.030. Epub 2022 Mar 12. J Hepatol. 2022. PMID: 35292350
Estrogen regulates Hippo signaling via GPER in breast cancer.
Zhou X, Wang S, Wang Z, Feng X, Liu P, Lv XB, Li F, Yu FX, Sun Y, Yuan H, Zhu H, Xiong Y, Lei QY, Guan KL. Zhou X, et al. Among authors: sun y. J Clin Invest. 2015 May;125(5):2123-35. doi: 10.1172/JCI79573. Epub 2015 Apr 20. J Clin Invest. 2015. PMID: 25893606 Free PMC article.
Endothelin Promotes Colorectal Tumorigenesis by Activating YAP/TAZ.
Wang Z, Liu P, Zhou X, Wang T, Feng X, Sun YP, Xiong Y, Yuan HX, Guan KL. Wang Z, et al. Among authors: sun yp. Cancer Res. 2017 May 1;77(9):2413-2423. doi: 10.1158/0008-5472.CAN-16-3229. Epub 2017 Mar 1. Cancer Res. 2017. PMID: 28249901 Free PMC article.
SIRT5 inhibits peroxisomal ACOX1 to prevent oxidative damage and is downregulated in liver cancer.
Chen XF, Tian MX, Sun RQ, Zhang ML, Zhou LS, Jin L, Chen LL, Zhou WJ, Duan KL, Chen YJ, Gao C, Cheng ZL, Wang F, Zhang JY, Sun YP, Yu HX, Zhao YZ, Yang Y, Liu WR, Shi YH, Xiong Y, Guan KL, Ye D. Chen XF, et al. Among authors: sun rq, sun yp. EMBO Rep. 2018 May;19(5):e45124. doi: 10.15252/embr.201745124. Epub 2018 Feb 28. EMBO Rep. 2018. PMID: 29491006 Free PMC article.
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