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A stromal cell population that inhibits adipogenesis in mammalian fat depots.
Schwalie PC, Dong H, Zachara M, Russeil J, Alpern D, Akchiche N, Caprara C, Sun W, Schlaudraff KU, Soldati G, Wolfrum C, Deplancke B. Schwalie PC, et al. Among authors: sun w. Nature. 2018 Jul;559(7712):103-108. doi: 10.1038/s41586-018-0226-8. Epub 2018 Jun 20. Nature. 2018. PMID: 29925944
Cold-induced epigenetic programming of the sperm enhances brown adipose tissue activity in the offspring.
Sun W, Dong H, Becker AS, Dapito DH, Modica S, Grandl G, Opitz L, Efthymiou V, Straub LG, Sarker G, Balaz M, Balazova L, Perdikari A, Kiehlmann E, Bacanovic S, Zellweger C, Peleg-Raibstein D, Pelczar P, Reik W, Burger IA, von Meyenn F, Wolfrum C. Sun W, et al. Nat Med. 2018 Sep;24(9):1372-1383. doi: 10.1038/s41591-018-0102-y. Epub 2018 Jul 9. Nat Med. 2018. PMID: 29988127
Author Correction: Cold-induced epigenetic programming of the sperm enhances brown adipose tissue activity in the offspring.
Sun W, Dong H, Becker AS, Dapito DH, Modica S, Grandl G, Opitz L, Efthymiou V, Straub LG, Sarker G, Balaz M, Balazova L, Perdikari A, Kiehlmann E, Bacanovic S, Zellweger C, Peleg-Raibstein D, Pelczar P, Reik W, Burger IA, von Meyenn F, Wolfrum C. Sun W, et al. Nat Med. 2018 Nov;24(11):1776. doi: 10.1038/s41591-018-0162-z. Nat Med. 2018. PMID: 30087435
Publisher Correction: Cold-induced epigenetic programming of the sperm enhances brown adipose tissue activity in the offspring.
Sun W, Dong H, Becker AS, Dapito DH, Modica S, Grandl G, Opitz L, Efthymiou V, Straub LG, Sarker G, Balaz M, Balazova L, Perdikari A, Kiehlmann E, Bacanovic S, Zellweger C, Peleg-Raibstein D, Pelczar P, Reik W, Burger IA, von Meyenn F, Wolfrum C. Sun W, et al. Nat Med. 2018 Nov;24(11):1777. doi: 10.1038/s41591-018-0163-y. Nat Med. 2018. PMID: 30087436
snRNA-seq reveals a subpopulation of adipocytes that regulates thermogenesis.
Sun W, Dong H, Balaz M, Slyper M, Drokhlyansky E, Colleluori G, Giordano A, Kovanicova Z, Stefanicka P, Balazova L, Ding L, Husted AS, Rudofsky G, Ukropec J, Cinti S, Schwartz TW, Regev A, Wolfrum C. Sun W, et al. Nature. 2020 Nov;587(7832):98-102. doi: 10.1038/s41586-020-2856-x. Epub 2020 Oct 28. Nature. 2020. PMID: 33116305
Local acetate inhibits brown adipose tissue function.
Sun W, Dong H, Wolfrum C. Sun W, et al. Proc Natl Acad Sci U S A. 2021 Dec 7;118(49):e2116125118. doi: 10.1073/pnas.2116125118. Proc Natl Acad Sci U S A. 2021. PMID: 34845033 Free PMC article.
GPR180 is a component of TGFβ signalling that promotes thermogenic adipocyte function and mediates the metabolic effects of the adipocyte-secreted factor CTHRC1.
Balazova L, Balaz M, Horvath C, Horváth Á, Moser C, Kovanicova Z, Ghosh A, Ghoshdastider U, Efthymiou V, Kiehlmann E, Sun W, Dong H, Ding L, Amri EZ, Nuutila P, Virtanen KA, Niemi T, Ukropcova B, Ukropec J, Pelczar P, Lamla T, Hamilton B, Neubauer H, Wolfrum C. Balazova L, et al. Among authors: sun w. Nat Commun. 2021 Dec 8;12(1):7144. doi: 10.1038/s41467-021-27442-x. Nat Commun. 2021. PMID: 34880217 Free PMC article.
Identification of a regulatory pathway inhibiting adipogenesis via RSPO2.
Dong H, Sun W, Shen Y, Baláz M, Balázová L, Ding L, Löffler M, Hamilton B, Klöting N, Blüher M, Neubauer H, Klein H, Wolfrum C. Dong H, et al. Among authors: sun w. Nat Metab. 2022 Jan;4(1):90-105. doi: 10.1038/s42255-021-00509-1. Epub 2022 Jan 13. Nat Metab. 2022. PMID: 35027768 Free PMC article.
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