Sun SC - Search Results

1

FBXO38 mediates PD-1 ubiquitination and regulates anti-tumour immunity of T cells.

Meng X, Liu X, Guo X, Jiang S, Chen T, Hu Z, Liu H, Bai Y, Xue M, Hu R, Sun SC, Liu X, Zhou P, Huang X, Wei L, Yang W, Xu C. Meng X, et al. Among authors: sun sc. Nature. 2018 Dec;564(7734):130-135. doi: 10.1038/s41586-018-0756-0. Epub 2018 Nov 28. Nature. 2018. PMID: 30487606

2

Potentiating the antitumour response of CD8(+) T cells by modulating cholesterol metabolism.

Yang W, Bai Y, Xiong Y, Zhang J, Chen S, Zheng X, Meng X, Li L, Wang J, Xu C, Yan C, Wang L, Chang CC, Chang TY, Zhang T, Zhou P, Song BL, Liu W, Sun SC, Liu X, Li BL, Xu C. Yang W, et al. Among authors: sun sc. Nature. 2016 Mar 31;531(7596):651-5. doi: 10.1038/nature17412. Epub 2016 Mar 16. Nature. 2016. PMID: 26982734 Free PMC article.

3

OTUD7B controls non-canonical NF-κB activation through deubiquitination of TRAF3.

Hu H, Brittain GC, Chang JH, Puebla-Osorio N, Jin J, Zal A, Xiao Y, Cheng X, Chang M, Fu YX, Zal T, Zhu C, Sun SC. Hu H, et al. Among authors: sun sc. Nature. 2013 Feb 21;494(7437):371-4. doi: 10.1038/nature11831. Epub 2013 Jan 20. Nature. 2013. PMID: 23334419 Free PMC article.

4

Peli1 negatively regulates noncanonical NF-κB signaling to restrain systemic lupus erythematosus.

Liu J, Huang X, Hao S, Wang Y, Liu M, Xu J, Zhang X, Yu T, Gan S, Dai D, Luo X, Lu Q, Mao C, Zhang Y, Shen N, Li B, Huang M, Zhu X, Jin J, Cheng X, Sun SC, Xiao Y. Liu J, et al. Among authors: sun sc. Nat Commun. 2018 Mar 19;9(1):1136. doi: 10.1038/s41467-018-03530-3. Nat Commun. 2018. PMID: 29555915 Free PMC article.

5

The ubiquitin ligase Peli1 negatively regulates T cell activation and prevents autoimmunity.

Chang M, Jin W, Chang JH, Xiao Y, Brittain GC, Yu J, Zhou X, Wang YH, Cheng X, Li P, Rabinovich BA, Hwu P, Sun SC. Chang M, et al. Among authors: sun sc. Nat Immunol. 2011 Aug 28;12(10):1002-9. doi: 10.1038/ni.2090. Nat Immunol. 2011. PMID: 21874024 Free PMC article.

6

The deubiquitinase Otub1 controls the activation of CD8⁺ T cells and NK cells by regulating IL-15-mediated priming.

Zhou X, Yu J, Cheng X, Zhao B, Manyam GC, Zhang L, Schluns K, Li P, Wang J, Sun SC. Zhou X, et al. Among authors: sun sc. Nat Immunol. 2019 Jul;20(7):879-889. doi: 10.1038/s41590-019-0405-2. Epub 2019 Jun 10. Nat Immunol. 2019. PMID: 31182807 Free PMC article.

7

NF-κB-inducing kinase maintains T cell metabolic fitness in antitumor immunity.

Gu M, Zhou X, Sohn JH, Zhu L, Jie Z, Yang JY, Zheng X, Xie X, Yang J, Shi Y, Brightbill HD, Kim JB, Wang J, Cheng X, Sun SC. Gu M, et al. Among authors: sun sc. Nat Immunol. 2021 Feb;22(2):193-204. doi: 10.1038/s41590-020-00829-6. Epub 2021 Jan 4. Nat Immunol. 2021. PMID: 33398181 Free PMC article.

8

Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production.

Chang M, Jin W, Sun SC. Chang M, et al. Among authors: sun sc. Nat Immunol. 2009 Oct;10(10):1089-95. doi: 10.1038/ni.1777. Epub 2009 Sep 6. Nat Immunol. 2009. PMID: 19734906 Free PMC article.

9

USP15 stabilizes MDM2 to mediate cancer-cell survival and inhibit antitumor T cell responses.

Zou Q, Jin J, Hu H, Li HS, Romano S, Xiao Y, Nakaya M, Zhou X, Cheng X, Yang P, Lozano G, Zhu C, Watowich SS, Ullrich SE, Sun SC. Zou Q, et al. Among authors: sun sc. Nat Immunol. 2014 Jun;15(6):562-70. doi: 10.1038/ni.2885. Epub 2014 Apr 28. Nat Immunol. 2014. PMID: 24777531 Free PMC article.

10

STAT3 restrains RANK- and TLR4-mediated signalling by suppressing expression of the E2 ubiquitin-conjugating enzyme Ubc13.

Zhang H, Hu H, Greeley N, Jin J, Matthews AJ, Ohashi E, Caetano MS, Li HS, Wu X, Mandal PK, McMurray JS, Moghaddam SJ, Sun SC, Watowich SS. Zhang H, et al. Among authors: sun sc. Nat Commun. 2014 Dec 15;5:5798. doi: 10.1038/ncomms6798. Nat Commun. 2014. PMID: 25503582 Free PMC article.

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