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The Amygdala Noradrenergic System Is Compromised With Alcohol Use Disorder.
Varodayan FP, Patel RR, Matzeu A, Wolfe SA, Curley DE, Khom S, Gandhi PJ, Rodriguez L, Bajo M, D'Ambrosio S, Sun H, Kerr TM, Gonzales RA, Leggio L, Natividad LA, Haass-Koffler CL, Martin-Fardon R, Roberto M. Varodayan FP, et al. Among authors: sun h. Biol Psychiatry. 2022 Jun 15;91(12):1008-1018. doi: 10.1016/j.biopsych.2022.02.006. Epub 2022 Apr 13. Biol Psychiatry. 2022. PMID: 35430085 Free PMC article.
A closer look at alcohol-induced changes in the ghrelin system: novel insights from preclinical and clinical data.
Deschaine SL, Farokhnia M, Gregory-Flores A, Zallar LJ, You ZB, Sun H, Harvey DM, Marchette RCN, Tunstall BJ, Mani BK, Moose JE, Lee MR, Gardner E, Akhlaghi F, Roberto M, Hougland JL, Zigman JM, Koob GF, Vendruscolo LF, Leggio L. Deschaine SL, et al. Among authors: sun h. Addict Biol. 2022 Jan;27(1):e13033. doi: 10.1111/adb.13033. Epub 2021 Apr 27. Addict Biol. 2022. PMID: 33908131 Free PMC article. Clinical Trial.
Tacr1 gene variation and neurokinin 1 receptor expression is associated with antagonist efficacy in genetically selected alcohol-preferring rats.
Schank JR, Tapocik JD, Barbier E, Damadzic R, Eskay RL, Sun H, Rowe KE, King CE, Yao M, Flanigan ME, Solomon MG, Karlsson C, Cheng K, Rice KC, Heilig M. Schank JR, et al. Among authors: sun h. Biol Psychiatry. 2013 Apr 15;73(8):774-81. doi: 10.1016/j.biopsych.2012.12.027. Epub 2013 Feb 16. Biol Psychiatry. 2013. PMID: 23419547 Free PMC article.
Additive Effects of Stress and Alcohol Exposure on Accelerated Epigenetic Aging in Alcohol Use Disorder.
Jung J, McCartney DL, Wagner J, Yoo J, Bell AS, Mavromatis LA, Rosoff DB, Hodgkinson CA, Sun H, Schwandt M, Diazgranados N, Smith AK, Michopoulos V, Powers A, Stevens J, Bradley B, Fani N, Walker RM, Campbell A, Porteous DJ, McIntosh AM, Horvath S, Marioni RE, Evans KL, Goldman D, Lohoff FW. Jung J, et al. Among authors: sun h. Biol Psychiatry. 2023 Feb 15;93(4):331-341. doi: 10.1016/j.biopsych.2022.06.036. Epub 2022 Jul 16. Biol Psychiatry. 2023. PMID: 36182531 Free article.
Epigenome-wide association study and multi-tissue replication of individuals with alcohol use disorder: evidence for abnormal glucocorticoid signaling pathway gene regulation.
Lohoff FW, Roy A, Jung J, Longley M, Rosoff DB, Luo A, O'Connell E, Sorcher JL, Sun H, Schwandt M, Hodgkinson CA, Goldman D, Momenan R, McIntosh AM, Adams MJ, Walker RM, Evans KL, Porteous D, Smith AK, Lee J, Muench C, Charlet K, Clarke TK, Kaminsky ZA. Lohoff FW, et al. Among authors: sun h. Mol Psychiatry. 2021 Jun;26(6):2224-2237. doi: 10.1038/s41380-020-0734-4. Epub 2020 May 12. Mol Psychiatry. 2021. PMID: 32398718 Free PMC article.
Dependence-induced increase of alcohol self-administration and compulsive drinking mediated by the histone methyltransferase PRDM2.
Barbier E, Johnstone AL, Khomtchouk BB, Tapocik JD, Pitcairn C, Rehman F, Augier E, Borich A, Schank JR, Rienas CA, Van Booven DJ, Sun H, Nätt D, Wahlestedt C, Heilig M. Barbier E, et al. Among authors: sun h. Mol Psychiatry. 2017 Dec;22(12):1746-1758. doi: 10.1038/mp.2016.131. Epub 2016 Aug 30. Mol Psychiatry. 2017. PMID: 27573876 Free PMC article.
Methylomic profiling and replication implicates deregulation of PCSK9 in alcohol use disorder.
Lohoff FW, Sorcher JL, Rosen AD, Mauro KL, Fanelli RR, Momenan R, Hodgkinson CA, Vendruscolo LF, Koob GF, Schwandt M, George DT, Jones IS, Holmes A, Zhou Z, Xu MJ, Gao B, Sun H, Phillips MJ, Muench C, Kaminsky ZA. Lohoff FW, et al. Among authors: sun h. Mol Psychiatry. 2018 Sep;23(9):1900-1910. doi: 10.1038/mp.2017.168. Epub 2017 Aug 29. Mol Psychiatry. 2018. PMID: 28848234 Free PMC article.
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