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Beneficial Role of Erythrocyte Adenosine A2B Receptor-Mediated AMP-Activated Protein Kinase Activation in High-Altitude Hypoxia.
Liu H, Zhang Y, Wu H, D'Alessandro A, Yegutkin GG, Song A, Sun K, Li J, Cheng NY, Huang A, Edward Wen Y, Weng TT, Luo F, Nemkov T, Sun H, Kellems RE, Karmouty-Quintana H, Hansen KC, Zhao B, Subudhi AW, Jameson-Van Houten S, Julian CG, Lovering AT, Eltzschig HK, Blackburn MR, Roach RC, Xia Y. Liu H, et al. Among authors: sun k, sun h. Circulation. 2016 Aug 2;134(5):405-21. doi: 10.1161/CIRCULATIONAHA.116.021311. Circulation. 2016. PMID: 27482003 Free PMC article.
Erythrocyte adenosine A2B receptor prevents cognitive and auditory dysfunction by promoting hypoxic and metabolic reprogramming.
Qiang Q, Manalo JM, Sun H, Zhang Y, Song A, Wen AQ, Wen YE, Chen C, Liu H, Cui Y, Nemkov T, Reisz JA, Edwards Iii G, Perreira FA, Kellems RE, Soto C, D'Alessandro A, Xia Y. Qiang Q, et al. Among authors: sun h. PLoS Biol. 2021 Jun 17;19(6):e3001239. doi: 10.1371/journal.pbio.3001239. eCollection 2021 Jun. PLoS Biol. 2021. PMID: 34138843 Free PMC article.
Elevated ecto-5'-nucleotidase-mediated increased renal adenosine signaling via A2B adenosine receptor contributes to chronic hypertension.
Zhang W, Zhang Y, Wang W, Dai Y, Ning C, Luo R, Sun K, Glover L, Grenz A, Sun H, Tao L, Zhang W, Colgan SP, Blackburn MR, Eltzschig HK, Kellems RE, Xia Y. Zhang W, et al. Among authors: sun k, sun h. Circ Res. 2013 May 24;112(11):1466-78. doi: 10.1161/CIRCRESAHA.111.300166. Epub 2013 Apr 12. Circ Res. 2013. PMID: 23584256 Free PMC article.
Increased adenosine contributes to penile fibrosis, a dangerous feature of priapism, via A2B adenosine receptor signaling.
Wen J, Jiang X, Dai Y, Zhang Y, Tang Y, Sun H, Mi T, Phatarpekar PV, Kellems RE, Blackburn MR, Xia Y. Wen J, et al. Among authors: sun h. FASEB J. 2010 Mar;24(3):740-9. doi: 10.1096/fj.09-144147. Epub 2009 Oct 26. FASEB J. 2010. PMID: 19858092 Free PMC article.
Overall, our studies identify an essential role of increased adenosine in the pathogenesis of penile fibrosis via A(2B)R signaling and offer a potential target for prevention and treatment of penile fibrosis, a dangerous complication seen in priapism.-Wen, J., Jiang, X., Dai, Y., …
Overall, our studies identify an essential role of increased adenosine in the pathogenesis of penile fibrosis via A(2B)R signaling and offer …
Detrimental effects of adenosine signaling in sickle cell disease.
Zhang Y, Dai Y, Wen J, Zhang W, Grenz A, Sun H, Tao L, Lu G, Alexander DC, Milburn MV, Carter-Dawson L, Lewis DE, Zhang W, Eltzschig HK, Kellems RE, Blackburn MR, Juneja HS, Xia Y. Zhang Y, et al. Among authors: sun h. Nat Med. 2011 Jan;17(1):79-86. doi: 10.1038/nm.2280. Epub 2010 Dec 19. Nat Med. 2011. PMID: 21170046 Free PMC article.
Cadmium-induced ototoxicity in rat cochlear organotypic cultures.
Liu H, Ding D, Sun H, Jiang H, Wu X, Roth JA, Salvi R. Liu H, et al. Among authors: sun h. Neurotox Res. 2014 Aug;26(2):179-89. doi: 10.1007/s12640-014-9461-4. Epub 2014 Feb 28. Neurotox Res. 2014. PMID: 24577639 Free PMC article.
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