Sumner RP - Search Results

1

Disrupting HIV-1 capsid formation causes cGAS sensing of viral DNA.

Sumner RP, Harrison L, Touizer E, Peacock TP, Spencer M, Zuliani-Alvarez L, Towers GJ. Sumner RP, et al. EMBO J. 2020 Oct 15;39(20):e103958. doi: 10.15252/embj.2019103958. Epub 2020 Aug 27. EMBO J. 2020. PMID: 32852081 Free PMC article.

2

Are Evolution and the Intracellular Innate Immune System Key Determinants in HIV Transmission?

Sumner RP, Thorne LG, Fink DL, Khan H, Milne RS, Towers GJ. Sumner RP, et al. Front Immunol. 2017 Oct 6;8:1246. doi: 10.3389/fimmu.2017.01246. eCollection 2017. Front Immunol. 2017. PMID: 29056936 Free PMC article. Review.

3

Virulent Poxviruses Inhibit DNA Sensing by Preventing STING Activation.

Georgana I, Sumner RP, Towers GJ, Maluquer de Motes C. Georgana I, et al. Among authors: sumner rp. J Virol. 2018 Apr 27;92(10):e02145-17. doi: 10.1128/JVI.02145-17. Print 2018 May 15. J Virol. 2018. PMID: 29491158 Free PMC article.

4

KAP1 regulates endogenous retroviruses in adult human cells and contributes to innate immune control.

Tie CH, Fernandes L, Conde L, Robbez-Masson L, Sumner RP, Peacock T, Rodriguez-Plata MT, Mickute G, Gifford R, Towers GJ, Herrero J, Rowe HM. Tie CH, et al. Among authors: sumner rp. EMBO Rep. 2018 Oct;19(10):e45000. doi: 10.15252/embr.201745000. Epub 2018 Jul 30. EMBO Rep. 2018. PMID: 30061100 Free PMC article.

5

Lentiviral Vector Production Titer Is Not Limited in HEK293T by Induced Intracellular Innate Immunity.

Ferreira CB, Sumner RP, Rodriguez-Plata MT, Rasaiyaah J, Milne RS, Thrasher AJ, Qasim W, Towers GJ. Ferreira CB, et al. Among authors: sumner rp. Mol Ther Methods Clin Dev. 2019 Dec 24;17:209-219. doi: 10.1016/j.omtm.2019.11.021. eCollection 2020 Jun 12. Mol Ther Methods Clin Dev. 2019. PMID: 31970199 Free PMC article.

6

HIV-1 Vpr antagonizes innate immune activation by targeting karyopherin-mediated NF-κB/IRF3 nuclear transport.

Khan H, Sumner RP, Rasaiyaah J, Tan CP, Rodriguez-Plata MT, Van Tulleken C, Fink D, Zuliani-Alvarez L, Thorne L, Stirling D, Milne RS, Towers GJ. Khan H, et al. Among authors: sumner rp. Elife. 2020 Dec 10;9:e60821. doi: 10.7554/eLife.60821. Elife. 2020. PMID: 33300875 Free PMC article.

7

HIV-2/SIV Vpx antagonises NF-κB activation by targeting p65.

Fink DL, Cai J, Whelan MVX, Monit C, Maluquer de Motes C, Towers GJ, Sumner RP. Fink DL, et al. Among authors: sumner rp. Retrovirology. 2022 Jan 24;19(1):2. doi: 10.1186/s12977-021-00586-w. Retrovirology. 2022. PMID: 35073912 Free PMC article.

8

Disruption of the cGAS/STING axis does not impair sensing of MVA in BHK21 cells.

Hood AJM, Sumner RP, Maluquer de Motes C. Hood AJM, et al. Among authors: sumner rp. J Gen Virol. 2022 May;103(5). doi: 10.1099/jgv.0.001755. J Gen Virol. 2022. PMID: 35584007

9

Evasion of cGAS and TRIM5 defines pandemic HIV.

Zuliani-Alvarez L, Govasli ML, Rasaiyaah J, Monit C, Perry SO, Sumner RP, McAlpine-Scott S, Dickson C, Rifat Faysal KM, Hilditch L, Miles RJ, Bibollet-Ruche F, Hahn BH, Boecking T, Pinotsis N, James LC, Jacques DA, Towers GJ. Zuliani-Alvarez L, et al. Among authors: sumner rp. Nat Microbiol. 2022 Nov;7(11):1762-1776. doi: 10.1038/s41564-022-01247-0. Epub 2022 Oct 26. Nat Microbiol. 2022. PMID: 36289397 Free PMC article.

10

Vaccinia virus protein N2 is a nuclear IRF3 inhibitor that promotes virulence.

Ferguson BJ, Benfield CTO, Ren H, Lee VH, Frazer GL, Strnadova P, Sumner RP, Smith GL. Ferguson BJ, et al. Among authors: sumner rp. J Gen Virol. 2013 Sep;94(Pt 9):2070-2081. doi: 10.1099/vir.0.054114-0. Epub 2013 Jun 12. J Gen Virol. 2013. PMID: 23761407 Free PMC article.

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