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Discovery of new imidazotetrazinones with potential to overcome tumor resistance.
Eur J Med Chem. 2023 Sep 5;257:115507. doi: 10.1016/j.ejmech.2023.115507. Epub 2023 May 21.
Eur J Med Chem. 2023.
PMID: 37262998
Free article.
Synthesis and growth-inhibitory activities of imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamides related to the anti-tumour drug temozolomide, with appended silicon, benzyl and heteromethyl groups at the 3-position.
Cousin D, Hummersone MG, Bradshaw TD, Zhang J, Moody CJ, Foreiter MB, Summers HS, Lewis W, Wheelhouse RT, Stevens MFG.
Cousin D, et al. Among authors: summers hs.
Medchemcomm. 2018 Jan 19;9(3):545-553. doi: 10.1039/c7md00554g. eCollection 2018 Mar 1.
Medchemcomm. 2018.
PMID: 30108945
Free PMC article.
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Delivery of Temozolomide and N3-Propargyl Analog to Brain Tumors Using an Apoferritin Nanocage.
Bouzinab K, Summers HS, Stevens MFG, Moody CJ, Thomas NR, Gershkovich P, Weston N, Ashford MB, Bradshaw TD, Turyanska L.
Bouzinab K, et al. Among authors: summers hs.
ACS Appl Mater Interfaces. 2020 Mar 18;12(11):12609-12617. doi: 10.1021/acsami.0c01514. Epub 2020 Mar 4.
ACS Appl Mater Interfaces. 2020.
PMID: 32073826
Free article.
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In search of effective therapies to overcome resistance to Temozolomide in brain tumours.
Bouzinab K, Summers H, Zhang J, Stevens MFG, Moody CJ, Turyanska L, Thomas NR, Gershkovich P, Ashford MB, Vitterso E, Storer LCD, Grundy R, Bradshaw TD.
Bouzinab K, et al.
Cancer Drug Resist. 2019 Dec 19;2(4):1018-1031. doi: 10.20517/cdr.2019.64. eCollection 2019.
Cancer Drug Resist. 2019.
PMID: 35582280
Free PMC article.
Review.
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