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Page 1
Dealing with complexity: general discussion.
Afonso C, Barrow MP, Bell NGA, Davies AN, Duca D, Focsa C, Gauchotte-Lindsay C, Giusti P, Godfrey R, Goodacre R, Hawkes JA, Hertkorn N, Jansen JJ, Jones D, Kew W, Le Guennec A, Lubben A, Paša-Tolić L, Rodgers RP, Rüger CP, Schmitt-Kopplin P, Schoenmakers PJ, Sciarrone D, Summerfield S, Uhrín D, van Zelst FHM. Afonso C, et al. Among authors: summerfield s. Faraday Discuss. 2019 Aug 15;218(0):138-156. doi: 10.1039/C9FD90055A. Faraday Discuss. 2019. PMID: 31384874 No abstract available.
High resolution techniques: general discussion.
Adair E, Afonso C, Bell NGA, Davies AN, Delsuc MA, Godfrey R, Goodacre R, Hawkes JA, Hertkorn N, Jones D, Lameiras P, Le Guennec A, Lubben A, Nilsson M, Paša-Tolić L, Richards J, Rodgers RP, Rüger CP, Schmitt-Kopplin P, Schoenmakers PJ, Sidebottom P, Staerk D, Summerfield S, Uhrín D, van Delft P, van der Hooft JJJ, van Zelst FHM, Zherebker A. Adair E, et al. Among authors: summerfield s. Faraday Discuss. 2019 Aug 15;218(0):247-267. doi: 10.1039/c9fd90045d. Faraday Discuss. 2019. PMID: 31369012 No abstract available.
Data mining and visualisation: general discussion.
Afonso C, Barrow MP, Davies AN, Delsuc MA, Ebbels T, Fernandez-Lima F, Gauchotte-Lindsay C, Giusti P, Goodacre R, Hertkorn N, Jansen JJ, Jones D, Kew W, Kuhn S, Le Guennec A, Lubben A, Parkinson J, Paša-Tolić L, Rogers S, Rudd TR, Schoenmakers PJ, Sidebottom P, Summerfield S, Tinnevelt GH, Trifirò G, Trygg J, van der Hooft JJJ. Afonso C, et al. Among authors: summerfield s. Faraday Discuss. 2019 Aug 15;218(0):354-371. doi: 10.1039/C9FD90044F. Faraday Discuss. 2019. PMID: 31373341 No abstract available.
Future challenges and new approaches: general discussion.
Afonso C, Chaux C, Davies AN, Delsuc MA, Fernandez Lima F, Gauchotte-Lindsay C, Giusti P, Goodacre R, Hawkes JA, Hertkorn N, Jansen JJ, Kew W, Kuhn S, Lubben A, McGill D, Nilsson M, Parkinson J, Rodgers RP, Rogers S, Schmitt-Kopplin P, Schoenmakers PJ, Shintu L, Soong R, Summerfield S, Surman A, Uhrín D, van der Hooft JJJ. Afonso C, et al. Among authors: summerfield s. Faraday Discuss. 2019 Aug 15;218(0):505-523. doi: 10.1039/c9fd90046b. Faraday Discuss. 2019. PMID: 31380556 No abstract available.
2021 White Paper on Recent Issues in Bioanalysis: Mass Spec of Proteins, Extracellular Vesicles, CRISPR, Chiral Assays, Oligos; Nanomedicines Bioanalysis; ICH M10 Section 7.1; Non-Liquid & Rare Matrices; Regulatory Inputs (Part 1A - Recommendations on Endogenous Compounds, Small Molecules, Complex Methods, Regulated Mass Spec of Large Molecules, Small Molecule, PoC & Part 1B - Regulatory Agencies' Inputs on Bioanalysis, Biomarkers, Immunogenicity, Gene & Cell Therapy and Vaccine).
Kaur S, Alley SC, Szapacs M, Wilson A, Ciccimaro E, Su D, Henderson N, Chen L, Garofolo F, Hengel S, Jian W, Kellie JF, Lee A, Mehl J, Palandra J, Qiu H, Savoie N, Shakleya D, Staelens L, Sugimoto H, Sumner G, Welink J, Wheller R, Xue YJ, Zeng J, Zhang J, Zhou H, Wang J, Summerfield S, Kavetska O, Dillen L, Ramanathan R, Baratta M, Dasgupta A, Edmison A, Ferrari L, Fischer S, Fraier D, Haidar S, Heermeier K, James C, Ji A, Luo L, Lima Santos GM, Post N, Rosenbaum AI, Sporring S, Surapaneni S, Vinter S, Wan K, Woolf E, Kavetska O, Cho SJ, Kossary E, Prior S, Abhari MR, Soo C, Wang YM, Bandukwala A, Cherry E, Cludts I, Ghosh S, Hopper S, Ishii-Watabe A, Kirshner S, Maher K, Maxfield K, Pedras-Vasconcelos J, Saito Y, Smith D, Solstad T, Verthelyi D, Wadhwa M, Wagner L, Waxenecker G, Yan H, Zhang L. Kaur S, et al. Among authors: summerfield s. Bioanalysis. 2022 May;14(9):505-580. doi: 10.4155/bio-2022-0078. Epub 2022 May 17. Bioanalysis. 2022. PMID: 35578993 Free article.
Unbound Brain-to-Plasma Partition Coefficient, Kp,uu,brain-a Game Changing Parameter for CNS Drug Discovery and Development.
Loryan I, Reichel A, Feng B, Bundgaard C, Shaffer C, Kalvass C, Bednarczyk D, Morrison D, Lesuisse D, Hoppe E, Terstappen GC, Fischer H, Di L, Colclough N, Summerfield S, Buckley ST, Maurer TS, Fridén M. Loryan I, et al. Among authors: summerfield s. Pharm Res. 2022 Jul;39(7):1321-1341. doi: 10.1007/s11095-022-03246-6. Epub 2022 Apr 11. Pharm Res. 2022. PMID: 35411506 Free PMC article.
Free Drug Theory - No Longer Just a Hypothesis?
Summerfield SG, Yates JWT, Fairman DA. Summerfield SG, et al. Pharm Res. 2022 Feb;39(2):213-222. doi: 10.1007/s11095-022-03172-7. Epub 2022 Feb 2. Pharm Res. 2022. PMID: 35112229
In Vivo Half-Life Extension of BMP1/TLL Metalloproteinase Inhibitors Using Small-Molecule Human Serum Albumin Binders.
Vantourout JC, Mason AM, Yuen J, Simpson GL, Evindar G, Kuai L, Hobbs M, Edgar E, Needle S, Bai X, Wilson S, Scott-Stevens P, Traylen W, Lambert K, Young N, Bunally S, Summerfield SG, Snell R, Lad R, Shi E, Skinner S, Shewchuk L, Watson AJB, Chung CW, Pal S, Holt DA, Kallander LS, Prendergast J, Rivera K, Washburn DG, Harpel MR, Arico-Muendel C, Isidro-Llobet A. Vantourout JC, et al. Among authors: summerfield sg. Bioconjug Chem. 2021 Feb 17;32(2):279-289. doi: 10.1021/acs.bioconjchem.0c00662. Epub 2021 Feb 1. Bioconjug Chem. 2021. PMID: 33523652
2020 White Paper on Recent Issues in Bioanalysis: BMV of Hybrid Assays, Acoustic MS, HRMS, Data Integrity, Endogenous Compounds, Microsampling and Microbiome (Part 1 - Recommendations on Industry/Regulators Consensus on BMV of Biotherapeutics by LCMS, Advanced Application in Hybrid Assays, Regulatory Challenges in Mass Spec, Innovation in Small Molecules, Peptides and Oligos).
Neubert H, Alley SC, Lee A, Jian W, Buonarati M, Edmison A, Garofolo F, Gorovits B, Haidar S, Mylott B, Nouri P, Qian M, Vinter S, Voelker T, Welink J, Wu J, Yang E, Yu H, Evans C, Summerfield S, Wang J, Bateman K, Boer J, Dean B, Dillen L, Faustino P, Ferrari L, Hughes N, Luo L, Olah T, Post N, Spellman DS, Sydor J, Zhang H, Zhang J, Zhang J, Fandozzi C, Wilson A, Fraier D, Beaver CJ, Dandamudi S, Dasgupta A, Elliott R, Ji A, Li W, McGuinness M, Lima Santos GM, Mirza T, Savoie N, Shakleya D, Sporring S, Stojdl S, Sundman P, Tampal N, Woolf E. Neubert H, et al. Among authors: summerfield s. Bioanalysis. 2021 Feb;13(4):203-238. doi: 10.4155/bio-2020-0324. Epub 2021 Jan 20. Bioanalysis. 2021. PMID: 33470871 Free article.
57 results