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Page 1
MDM4 inhibition: a novel therapeutic strategy to reactivate p53 in hepatoblastoma.
Woodfield SE, Shi Y, Patel RH, Chen Z, Shah AP, Srivastava RK, Whitlock RS, Ibarra AM, Larson SR, Sarabia SF, Badachhape A, Starosolski Z, Ghaghada KB, Sumazin P, Annis DA, López-Terrada D, Vasudevan SA. Woodfield SE, et al. Among authors: sumazin p. Sci Rep. 2021 Feb 3;11(1):2967. doi: 10.1038/s41598-021-82542-4. Sci Rep. 2021. PMID: 33536467 Free PMC article.
Novel patient-derived xenograft and cell line models for therapeutic testing of pediatric liver cancer.
Bissig-Choisat B, Kettlun-Leyton C, Legras XD, Zorman B, Barzi M, Chen LL, Amin MD, Huang YH, Pautler RG, Hampton OA, Prakash MM, Yang D, Borowiak M, Muzny D, Doddapaneni HV, Hu J, Shi Y, Gaber MW, Hicks MJ, Thompson PA, Lu Y, Mills GB, Finegold M, Goss JA, Parsons DW, Vasudevan SA, Sumazin P, López-Terrada D, Bissig KD. Bissig-Choisat B, et al. Among authors: sumazin p. J Hepatol. 2016 Aug;65(2):325-33. doi: 10.1016/j.jhep.2016.04.009. Epub 2016 Apr 23. J Hepatol. 2016. PMID: 27117591 Free PMC article.
Genomic analysis of hepatoblastoma identifies distinct molecular and prognostic subgroups.
Sumazin P, Chen Y, Treviño LR, Sarabia SF, Hampton OA, Patel K, Mistretta TA, Zorman B, Thompson P, Heczey A, Comerford S, Wheeler DA, Chintagumpala M, Meyers R, Rakheja D, Finegold MJ, Tomlinson G, Parsons DW, López-Terrada D. Sumazin P, et al. Hepatology. 2017 Jan;65(1):104-121. doi: 10.1002/hep.28888. Epub 2016 Nov 29. Hepatology. 2017. PMID: 27775819
Integrative analysis identifies lincRNAs up- and downstream of neuroblastoma driver genes.
Rombaut D, Chiu HS, Decaesteker B, Everaert C, Yigit N, Peltier A, Janoueix-Lerosey I, Bartenhagen C, Fischer M, Roberts S, D'Haene N, De Preter K, Speleman F, Denecker G, Sumazin P, Vandesompele J, Lefever S, Mestdagh P. Rombaut D, et al. Among authors: sumazin p. Sci Rep. 2019 Apr 5;9(1):5685. doi: 10.1038/s41598-019-42107-y. Sci Rep. 2019. PMID: 30952905 Free PMC article.
Restoration of the molecular clock is tumor suppressive in neuroblastoma.
Moreno-Smith M, Milazzo G, Tao L, Fekry B, Zhu B, Mohammad MA, Di Giacomo S, Borkar R, Reddy KRK, Capasso M, Vasudevan SA, Sumazin P, Hicks J, Putluri N, Perini G, Eckel-Mahan K, Burris TP, Barbieri E. Moreno-Smith M, et al. Among authors: sumazin p. Nat Commun. 2021 Jun 28;12(1):4006. doi: 10.1038/s41467-021-24196-4. Nat Commun. 2021. PMID: 34183658 Free PMC article.
CHAF1A Blocks Neuronal Differentiation and Promotes Neuroblastoma Oncogenesis via Metabolic Reprogramming.
Tao L, Moreno-Smith M, Ibarra-García-Padilla R, Milazzo G, Drolet NA, Hernandez BE, Oh YS, Patel I, Kim JJ, Zorman B, Patel T, Kamal AHM, Zhao Y, Hicks J, Vasudevan SA, Putluri N, Coarfa C, Sumazin P, Perini G, Parchem RJ, Uribe RA, Barbieri E. Tao L, et al. Among authors: sumazin p. Adv Sci (Weinh). 2021 Oct;8(19):e2005047. doi: 10.1002/advs.202005047. Epub 2021 Aug 8. Adv Sci (Weinh). 2021. PMID: 34365742 Free PMC article.
Author Correction: MDM4 inhibition: a novel therapeutic strategy to reactivate p53 in hepatoblastoma.
Woodfield SE, Shi Y, Patel RH, Chen Z, Shah AP, Srivastava RK, Whitlock RS, Ibarra AM, Larson SR, Sarabia SF, Badachhape A, Starosolski Z, Ghaghada KB, Sumazin P, Annis DA, López-Terrada D, Vasudevan SA. Woodfield SE, et al. Among authors: sumazin p. Sci Rep. 2021 Oct 1;11(1):19916. doi: 10.1038/s41598-021-98174-7. Sci Rep. 2021. PMID: 34599198 Free PMC article. No abstract available.
HepT1-derived murine models of high-risk hepatoblastoma display vascular invasion, metastasis, and circulating tumor cells.
Woodfield SE, Mistretta BJ, Patel RH, Ibarra AM, Fisher KE, Sarabia SF, Gandhi I, Reuther J, Starosolski Z, Badachhape A, Epps J, Zorman B, Shah AP, Larson SR, Srivastava RK, Shi Y, Espinoza AF, Govindu SR, Whitlock RS, Holloway K, Roy A, Sumazin P, Ghaghada KB, Lopez-Terrada D, Gunaratne PH, Vasudevan SA. Woodfield SE, et al. Among authors: sumazin p. Biol Open. 2022 Sep 15;11(9):bio058973. doi: 10.1242/bio.058973. Epub 2022 Sep 12. Biol Open. 2022. PMID: 35451474 Free PMC article.
Hepatoblastomas with carcinoma features represent a biological spectrum of aggressive neoplasms in children and young adults.
Sumazin P, Peters TL, Sarabia SF, Kim HR, Urbicain M, Hollingsworth EF, Alvarez KR, Perez CR, Pozza A, Najaf Panah MJ, Epps JL, Scorsone K, Zorman B, Katzenstein H, O'Neill AF, Meyers R, Tiao G, Geller J, Ranganathan S, Rangaswami AA, Woodfield SE, Goss JA, Vasudevan SA, Heczey A, Roy A, Fisher KE, Alaggio R, Patel KR, Finegold MJ, López-Terrada DH. Sumazin P, et al. J Hepatol. 2022 Oct;77(4):1026-1037. doi: 10.1016/j.jhep.2022.04.035. Epub 2022 May 14. J Hepatol. 2022. PMID: 35577029 Free PMC article.
76 results