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The effects of caloric restriction on adipose tissue and metabolic health are sex- and age-dependent.
Suchacki KJ, Thomas BJ, Ikushima YM, Chen KC, Fyfe C, Tavares AAS, Sulston RJ, Lovdel A, Woodward HJ, Han X, Mattiucci D, Brain EJ, Alcaide-Corral CJ, Kobayashi H, Gray GA, Whitfield PD, Stimson RH, Morton NM, Johnstone AM, Cawthorn WP. Suchacki KJ, et al. Among authors: sulston rj. Elife. 2023 Apr 25;12:e88080. doi: 10.7554/eLife.88080. Elife. 2023. PMID: 37096321 Free PMC article.
Bone marrow adipose tissue is a unique adipose subtype with distinct roles in glucose homeostasis.
Suchacki KJ, Tavares AAS, Mattiucci D, Scheller EL, Papanastasiou G, Gray C, Sinton MC, Ramage LE, McDougald WA, Lovdel A, Sulston RJ, Thomas BJ, Nicholson BM, Drake AJ, Alcaide-Corral CJ, Said D, Poloni A, Cinti S, Macpherson GJ, Dweck MR, Andrews JPM, Williams MC, Wallace RJ, van Beek EJR, MacDougald OA, Morton NM, Stimson RH, Cawthorn WP. Suchacki KJ, et al. Among authors: sulston rj. Nat Commun. 2020 Jun 18;11(1):3097. doi: 10.1038/s41467-020-16878-2. Nat Commun. 2020. PMID: 32555194 Free PMC article.
Expansion of Bone Marrow Adipose Tissue During Caloric Restriction Is Associated With Increased Circulating Glucocorticoids and Not With Hypoleptinemia.
Cawthorn WP, Scheller EL, Parlee SD, Pham HA, Learman BS, Redshaw CM, Sulston RJ, Burr AA, Das AK, Simon BR, Mori H, Bree AJ, Schell B, Krishnan V, MacDougald OA. Cawthorn WP, et al. Among authors: sulston rj. Endocrinology. 2016 Feb;157(2):508-21. doi: 10.1210/en.2015-1477. Epub 2015 Dec 22. Endocrinology. 2016. PMID: 26696121 Free PMC article.