Sullivan PM - Search Results

1

ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy.

Shi Y, Yamada K, Liddelow SA, Smith ST, Zhao L, Luo W, Tsai RM, Spina S, Grinberg LT, Rojas JC, Gallardo G, Wang K, Roh J, Robinson G, Finn MB, Jiang H, Sullivan PM, Baufeld C, Wood MW, Sutphen C, McCue L, Xiong C, Del-Aguila JL, Morris JC, Cruchaga C; Alzheimer’s Disease Neuroimaging Initiative; Fagan AM, Miller BL, Boxer AL, Seeley WW, Butovsky O, Barres BA, Paul SM, Holtzman DM. Shi Y, et al. Among authors: sullivan pm. Nature. 2017 Sep 28;549(7673):523-527. doi: 10.1038/nature24016. Epub 2017 Sep 20. Nature. 2017. PMID: 28959956 Free PMC article.

2

Purification and characterization of astrocyte-secreted apolipoprotein E and J-containing lipoproteins from wild-type and human apoE transgenic mice.

DeMattos RB, Brendza RP, Heuser JE, Kierson M, Cirrito JR, Fryer J, Sullivan PM, Fagan AM, Han X, Holtzman DM. DeMattos RB, et al. Among authors: sullivan pm. Neurochem Int. 2001 Nov-Dec;39(5-6):415-25. doi: 10.1016/s0197-0186(01)00049-3. Neurochem Int. 2001. PMID: 11578777

3

Human apolipoprotein E4 alters the amyloid-beta 40:42 ratio and promotes the formation of cerebral amyloid angiopathy in an amyloid precursor protein transgenic model.

Fryer JD, Simmons K, Parsadanian M, Bales KR, Paul SM, Sullivan PM, Holtzman DM. Fryer JD, et al. Among authors: sullivan pm. J Neurosci. 2005 Mar 16;25(11):2803-10. doi: 10.1523/JNEUROSCI.5170-04.2005. J Neurosci. 2005. PMID: 15772340 Free PMC article.

4

Production and characterization of astrocyte-derived human apolipoprotein E isoforms from immortalized astrocytes and their interactions with amyloid-beta.

Morikawa M, Fryer JD, Sullivan PM, Christopher EA, Wahrle SE, DeMattos RB, O'Dell MA, Fagan AM, Lashuel HA, Walz T, Asai K, Holtzman DM. Morikawa M, et al. Among authors: sullivan pm. Neurobiol Dis. 2005 Jun-Jul;19(1-2):66-76. doi: 10.1016/j.nbd.2004.11.005. Neurobiol Dis. 2005. PMID: 15837562

5

The low density lipoprotein receptor regulates the level of central nervous system human and murine apolipoprotein E but does not modify amyloid plaque pathology in PDAPP mice.

Fryer JD, Demattos RB, McCormick LM, O'Dell MA, Spinner ML, Bales KR, Paul SM, Sullivan PM, Parsadanian M, Bu G, Holtzman DM. Fryer JD, et al. Among authors: sullivan pm. J Biol Chem. 2005 Jul 8;280(27):25754-9. doi: 10.1074/jbc.M502143200. Epub 2005 May 11. J Biol Chem. 2005. PMID: 15888448 Free article.

6

APOE genotype affects outcome in a murine model of sepsis: implications for a new treatment strategy.

Wang H, Christensen DJ, Vitek MP, Sullivan PM, Laskowitz DT. Wang H, et al. Among authors: sullivan pm. Anaesth Intensive Care. 2009 Jan;37(1):38-45. doi: 10.1177/0310057X0903700111. Anaesth Intensive Care. 2009. PMID: 19157344

7

Reduced levels of human apoE4 protein in an animal model of cognitive impairment.

Sullivan PM, Han B, Liu F, Mace BE, Ervin JF, Wu S, Koger D, Paul S, Bales KR. Sullivan PM, et al. Neurobiol Aging. 2011 May;32(5):791-801. doi: 10.1016/j.neurobiolaging.2009.05.011. Epub 2009 Jul 4. Neurobiol Aging. 2011. PMID: 19577821

8

Emergence of a seizure phenotype in aged apolipoprotein epsilon 4 targeted replacement mice.

Hunter JM, Cirrito JR, Restivo JL, Kinley RD, Sullivan PM, Holtzman DM, Koger D, Delong C, Lin S, Zhao L, Liu F, Bales K, Paul SM. Hunter JM, et al. Among authors: sullivan pm. Brain Res. 2012 Jul 27;1467:120-32. doi: 10.1016/j.brainres.2012.05.048. Epub 2012 Jun 5. Brain Res. 2012. PMID: 22682924

9

Blocking the interaction between apolipoprotein E and Aβ reduces intraneuronal accumulation of Aβ and inhibits synaptic degeneration.

Kuszczyk MA, Sanchez S, Pankiewicz J, Kim J, Duszczyk M, Guridi M, Asuni AA, Sullivan PM, Holtzman DM, Sadowski MJ. Kuszczyk MA, et al. Among authors: sullivan pm. Am J Pathol. 2013 May;182(5):1750-68. doi: 10.1016/j.ajpath.2013.01.034. Epub 2013 Mar 13. Am J Pathol. 2013. PMID: 23499462 Free PMC article.

10

Blocking the apoE/Aβ interaction ameliorates Aβ-related pathology in APOE ε2 and ε4 targeted replacement Alzheimer model mice.

Pankiewicz JE, Guridi M, Kim J, Asuni AA, Sanchez S, Sullivan PM, Holtzman DM, Sadowski MJ. Pankiewicz JE, et al. Among authors: sullivan pm. Acta Neuropathol Commun. 2014 Jun 28;2:75. doi: 10.1186/s40478-014-0075-0. Acta Neuropathol Commun. 2014. PMID: 24972680 Free PMC article.

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