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The importance of serine metabolism in cancer.
Mattaini KR, Sullivan MR, Vander Heiden MG. Mattaini KR, et al. Among authors: sullivan mr. J Cell Biol. 2016 Aug 1;214(3):249-57. doi: 10.1083/jcb.201604085. Epub 2016 Jul 25. J Cell Biol. 2016. PMID: 27458133 Free PMC article. Review.
When cancer needs what's non-essential.
Sullivan MR, Vander Heiden MG. Sullivan MR, et al. Nat Cell Biol. 2017 May;19(5):418-420. doi: 10.1038/ncb3523. Epub 2017 Apr 19. Nat Cell Biol. 2017. PMID: 28422952
Serine Synthesis via PHGDH Is Essential for Heme Production in Endothelial Cells.
Vandekeere S, Dubois C, Kalucka J, Sullivan MR, García-Caballero M, Goveia J, Chen R, Diehl FF, Bar-Lev L, Souffreau J, Pircher A, Kumar S, Vinckier S, Hirabayashi Y, Furuya S, Schoonjans L, Eelen G, Ghesquière B, Keshet E, Li X, Vander Heiden MG, Dewerchin M, Carmeliet P. Vandekeere S, et al. Among authors: sullivan mr. Cell Metab. 2018 Oct 2;28(4):573-587.e13. doi: 10.1016/j.cmet.2018.06.009. Epub 2018 Jul 12. Cell Metab. 2018. PMID: 30017355 Free article.
Yap regulates glucose utilization and sustains nucleotide synthesis to enable organ growth.
Cox AG, Tsomides A, Yimlamai D, Hwang KL, Miesfeld J, Galli GG, Fowl BH, Fort M, Ma KY, Sullivan MR, Hosios AM, Snay E, Yuan M, Brown KK, Lien EC, Chhangawala S, Steinhauser ML, Asara JM, Houvras Y, Link B, Vander Heiden MG, Camargo FD, Goessling W. Cox AG, et al. Among authors: sullivan mr. EMBO J. 2018 Nov 15;37(22):e100294. doi: 10.15252/embj.2018100294. Epub 2018 Oct 22. EMBO J. 2018. PMID: 30348863 Free PMC article.
Determinants of nutrient limitation in cancer.
Sullivan MR, Vander Heiden MG. Sullivan MR, et al. Crit Rev Biochem Mol Biol. 2019 Jun;54(3):193-207. doi: 10.1080/10409238.2019.1611733. Epub 2019 Jun 4. Crit Rev Biochem Mol Biol. 2019. PMID: 31162937 Free PMC article. Review.
Increased PHGDH expression promotes aberrant melanin accumulation.
Mattaini KR, Sullivan MR, Lau AN, Fiske BP, Bronson RT, Vander Heiden MG. Mattaini KR, et al. Among authors: sullivan mr. BMC Cancer. 2019 Jul 22;19(1):723. doi: 10.1186/s12885-019-5933-5. BMC Cancer. 2019. PMID: 31331318 Free PMC article.
Deoxycytidine Release from Pancreatic Stellate Cells Promotes Gemcitabine Resistance.
Dalin S, Sullivan MR, Lau AN, Grauman-Boss B, Mueller HS, Kreidl E, Fenoglio S, Luengo A, Lees JA, Vander Heiden MG, Lauffenburger DA, Hemann MT. Dalin S, et al. Among authors: sullivan mr. Cancer Res. 2019 Nov 15;79(22):5723-5733. doi: 10.1158/0008-5472.CAN-19-0960. Epub 2019 Sep 4. Cancer Res. 2019. PMID: 31484670 Free PMC article.
79 results