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Fumonisins disrupt sphingolipid metabolism, folate transport, and neural tube development in embryo culture and in vivo: a potential risk factor for human neural tube defects among populations consuming fumonisin-contaminated maize.
Marasas WF, Riley RT, Hendricks KA, Stevens VL, Sadler TW, Gelineau-van Waes J, Missmer SA, Cabrera J, Torres O, Gelderblom WC, Allegood J, Martínez C, Maddox J, Miller JD, Starr L, Sullards MC, Roman AV, Voss KA, Wang E, Merrill AH Jr. Marasas WF, et al. Among authors: sullards mc. J Nutr. 2004 Apr;134(4):711-6. doi: 10.1093/jn/134.4.711. J Nutr. 2004. PMID: 15051815 Free article. Review.
Ceramide synthase inhibition by fumonisin B1 causes accumulation of 1-deoxysphinganine: a novel category of bioactive 1-deoxysphingoid bases and 1-deoxydihydroceramides biosynthesized by mammalian cell lines and animals.
Zitomer NC, Mitchell T, Voss KA, Bondy GS, Pruett ST, Garnier-Amblard EC, Liebeskind LS, Park H, Wang E, Sullards MC, Merrill AH Jr, Riley RT. Zitomer NC, et al. Among authors: sullards mc. J Biol Chem. 2009 Feb 20;284(8):4786-95. doi: 10.1074/jbc.M808798200. Epub 2008 Dec 18. J Biol Chem. 2009. PMID: 19095642 Free PMC article.
Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 (LAG1), regulates N-stearoyl-sphinganine (C18-(dihydro)ceramide) synthesis in a fumonisin B1-independent manner in mammalian cells.
Venkataraman K, Riebeling C, Bodennec J, Riezman H, Allegood JC, Sullards MC, Merrill AH Jr, Futerman AH. Venkataraman K, et al. Among authors: sullards mc. J Biol Chem. 2002 Sep 20;277(38):35642-9. doi: 10.1074/jbc.M205211200. Epub 2002 Jun 24. J Biol Chem. 2002. PMID: 12105227 Free article.
55 results