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Rufomycin Targets ClpC1 Proteolysis in Mycobacterium tuberculosis and M. abscessus.
Choules MP, Wolf NM, Lee H, Anderson JR, Grzelak EM, Wang Y, Ma R, Gao W, McAlpine JB, Jin YY, Cheng J, Lee H, Suh JW, Duc NM, Paik S, Choe JH, Jo EK, Chang CL, Lee JS, Jaki BU, Pauli GF, Franzblau SG, Cho S. Choules MP, et al. Among authors: suh jw. Antimicrob Agents Chemother. 2019 Feb 26;63(3):e02204-18. doi: 10.1128/AAC.02204-18. Print 2019 Mar. Antimicrob Agents Chemother. 2019. PMID: 30602512 Free PMC article.
Discovery and characterization of the tuberculosis drug lead ecumicin.
Gao W, Kim JY, Chen SN, Cho SH, Choi J, Jaki BU, Jin YY, Lankin DC, Lee JE, Lee SY, McAlpine JB, Napolitano JG, Franzblau SG, Suh JW, Pauli GF. Gao W, et al. Among authors: suh jw. Org Lett. 2014 Dec 5;16(23):6044-7. doi: 10.1021/ol5026603. Epub 2014 Nov 19. Org Lett. 2014. PMID: 25409285 Free PMC article.
The cyclic peptide ecumicin targeting ClpC1 is active against Mycobacterium tuberculosis in vivo.
Gao W, Kim JY, Anderson JR, Akopian T, Hong S, Jin YY, Kandror O, Kim JW, Lee IA, Lee SY, McAlpine JB, Mulugeta S, Sunoqrot S, Wang Y, Yang SH, Yoon TM, Goldberg AL, Pauli GF, Suh JW, Franzblau SG, Cho S. Gao W, et al. Among authors: suh jw. Antimicrob Agents Chemother. 2015 Feb;59(2):880-9. doi: 10.1128/AAC.04054-14. Epub 2014 Nov 24. Antimicrob Agents Chemother. 2015. PMID: 25421483 Free PMC article.
436 results