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Matrix metalloproteinase-9 activates TGF-β and stimulates fibroblast contraction of collagen gels.
Kobayashi T, Kim H, Liu X, Sugiura H, Kohyama T, Fang Q, Wen FQ, Abe S, Wang X, Atkinson JJ, Shipley JM, Senior RM, Rennard SI. Kobayashi T, et al. Among authors: sugiura h. Am J Physiol Lung Cell Mol Physiol. 2014 Jun 1;306(11):L1006-15. doi: 10.1152/ajplung.00015.2014. Epub 2014 Apr 4. Am J Physiol Lung Cell Mol Physiol. 2014. PMID: 24705725 Free PMC article.
Smad3 mediates TGF-beta1-induced collagen gel contraction by human lung fibroblasts.
Kobayashi T, Liu X, Wen FQ, Kohyama T, Shen L, Wang XQ, Hashimoto M, Mao L, Togo S, Kawasaki S, Sugiura H, Kamio K, Rennard SI. Kobayashi T, et al. Among authors: sugiura h. Biochem Biophys Res Commun. 2006 Jan 6;339(1):290-5. doi: 10.1016/j.bbrc.2005.10.209. Epub 2005 Nov 15. Biochem Biophys Res Commun. 2006. PMID: 16298342
Prostacyclin analogs stimulate VEGF production from human lung fibroblasts in culture.
Kamio K, Sato T, Liu X, Sugiura H, Togo S, Kobayashi T, Kawasaki S, Wang X, Mao L, Ahn Y, Holz O, Magnussen H, Rennard SI. Kamio K, et al. Among authors: sugiura h. Am J Physiol Lung Cell Mol Physiol. 2008 Jun;294(6):L1226-32. doi: 10.1152/ajplung.00129.2007. Epub 2008 Apr 18. Am J Physiol Lung Cell Mol Physiol. 2008. PMID: 18424619 Free article.
PDE4 inhibitors roflumilast and rolipram augment PGE2 inhibition of TGF-{beta}1-stimulated fibroblasts.
Togo S, Liu X, Wang X, Sugiura H, Kamio K, Kawasaki S, Kobayashi T, Ertl RF, Ahn Y, Holz O, Magnussen H, Fredriksson K, Skold CM, Rennard SI. Togo S, et al. Among authors: sugiura h. Am J Physiol Lung Cell Mol Physiol. 2009 Jun;296(6):L959-69. doi: 10.1152/ajplung.00508.2007. Epub 2009 Mar 20. Am J Physiol Lung Cell Mol Physiol. 2009. PMID: 19304913 Free article.
Sphingosylphosphorylcholine induces α-smooth muscle actin expression in human lung fibroblasts and fibroblast-mediated gel contraction via S1P2 receptor and Rho/Rho-kinase pathway.
Wang XQ, Mao LJ, Fang QH, Kobayashi T, Kim HJ, Sugiura H, Kawasaki S, Togo S, Kamio K, Liu X, Rennard SI. Wang XQ, et al. Among authors: sugiura h. Prostaglandins Other Lipid Mediat. 2014 Jan;108:23-30. doi: 10.1016/j.prostaglandins.2014.02.002. Epub 2014 Mar 5. Prostaglandins Other Lipid Mediat. 2014. PMID: 24614064
943 results