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Rheinanthrone, a metabolite of sennoside A, triggers macrophage activation to decrease aquaporin-3 expression in the colon, causing the laxative effect of rhubarb extract.
Kon R, Ikarashi N, Nagoya C, Takayama T, Kusunoki Y, Ishii M, Ueda H, Ochiai W, Machida Y, Sugita K, Sugiyama K. Kon R, et al. Among authors: sugita k. J Ethnopharmacol. 2014 Feb 27;152(1):190-200. doi: 10.1016/j.jep.2013.12.055. Epub 2014 Jan 8. J Ethnopharmacol. 2014. PMID: 24412547
Facile Total Synthesis of (+)-Spinoxazine B.
Iwata M, Kuwabara M, Matsuzawa A, Sugita K. Iwata M, et al. Among authors: sugita k. Chem Pharm Bull (Tokyo). 2018;66(12):1196-1198. doi: 10.1248/cpb.c18-00693. Chem Pharm Bull (Tokyo). 2018. PMID: 30504633 Free article.
Further investigation of the rapid-onset and short-duration action of the G protein-biased μ-ligand oliceridine.
Mori T, Takemura Y, Arima T, Iwase Y, Narita M, Miyano K, Hamada Y, Suda Y, Matsuzawa A, Sugita K, Matsumura S, Sasaki S, Yamauchi T, Higashiyama K, Uezono Y, Yamazaki M, Kuzumaki N, Narita M. Mori T, et al. Among authors: sugita k. Biochem Biophys Res Commun. 2021 Jan 1;534:988-994. doi: 10.1016/j.bbrc.2020.10.053. Epub 2020 Nov 1. Biochem Biophys Res Commun. 2021. PMID: 33139013
Convergent total synthesis of corallocin A.
Mashiko T, Nakazato Y, Katsumura Y, Kasamatsu A, Adachi S, Kamo S, Matsuzawa A, Sugita K. Mashiko T, et al. Among authors: sugita k. Org Biomol Chem. 2021 Jun 16;19(23):5127-5132. doi: 10.1039/d1ob00451d. Org Biomol Chem. 2021. PMID: 34019614
1,435 results