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10-oxo-12(Z)-octadecenoic acid, a linoleic acid metabolite produced by gut lactic acid bacteria, potently activates PPARγ and stimulates adipogenesis.
Goto T, Kim YI, Furuzono T, Takahashi N, Yamakuni K, Yang HE, Li Y, Ohue R, Nomura W, Sugawara T, Yu R, Kitamura N, Park SB, Kishino S, Ogawa J, Kawada T. Goto T, et al. Among authors: sugawara t. Biochem Biophys Res Commun. 2015 Apr 17;459(4):597-603. doi: 10.1016/j.bbrc.2015.02.154. Epub 2015 Mar 5. Biochem Biophys Res Commun. 2015. PMID: 25749343
Gut Microbial Fatty Acid Metabolites Reduce Triacylglycerol Levels in Hepatocytes.
Nanthirudjanar T, Furumoto H, Zheng J, Kim YI, Goto T, Takahashi N, Kawada T, Park SB, Hirata A, Kitamura N, Kishino S, Ogawa J, Hirata T, Sugawara T. Nanthirudjanar T, et al. Among authors: sugawara t. Lipids. 2015 Nov;50(11):1093-102. doi: 10.1007/s11745-015-4067-z. Epub 2015 Sep 23. Lipids. 2015. PMID: 26399511 Free article.
10-Oxo-trans-11-octadecenoic acid generated from linoleic acid by a gut lactic acid bacterium Lactobacillus plantarum is cytoprotective against oxidative stress.
Furumoto H, Nanthirudjanar T, Kume T, Izumi Y, Park SB, Kitamura N, Kishino S, Ogawa J, Hirata T, Sugawara T. Furumoto H, et al. Among authors: sugawara t. Toxicol Appl Pharmacol. 2016 Apr 1;296:1-9. doi: 10.1016/j.taap.2016.02.012. Epub 2016 Feb 12. Toxicol Appl Pharmacol. 2016. PMID: 26879219
1,286 results