Sugahara K - Search Results

1

A new phenylpyrazoleanilide, y-320, inhibits interleukin 17 production and ameliorates collagen-induced arthritis in mice and cynomolgus monkeys.

Ushio H, Ishibuchi S, Oshita K, Seki N, Kataoka H, Sugahara K, Adachi K, Chiba K. Ushio H, et al. Among authors: sugahara k. Pharmaceuticals (Basel). 2013 Dec 23;7(1):1-17. doi: 10.3390/ph7010001. Pharmaceuticals (Basel). 2013. PMID: 24366113 Free PMC article.

2

IL-17-Producing Vγ4+ γδ T Cells Require Sphingosine 1-Phosphate Receptor 1 for Their Egress from the Lymph Nodes under Homeostatic and Inflammatory Conditions.

Maeda Y, Seki N, Kataoka H, Takemoto K, Utsumi H, Fukunari A, Sugahara K, Chiba K. Maeda Y, et al. Among authors: sugahara k. J Immunol. 2015 Aug 15;195(4):1408-16. doi: 10.4049/jimmunol.1500599. Epub 2015 Jul 13. J Immunol. 2015. PMID: 26170380

3

FTY720, sphingosine 1-phosphate receptor modulator, ameliorates experimental autoimmune encephalomyelitis by inhibition of T cell infiltration.

Kataoka H, Sugahara K, Shimano K, Teshima K, Koyama M, Fukunari A, Chiba K. Kataoka H, et al. Among authors: sugahara k. Cell Mol Immunol. 2005 Dec;2(6):439-48. Cell Mol Immunol. 2005. PMID: 16426494 Free article.

4

Sphingosine 1-phosphate receptor type 1 regulates egress of mature T cells from mouse bone marrow.

Maeda Y, Seki N, Sato N, Sugahara K, Chiba K. Maeda Y, et al. Among authors: sugahara k. Int Immunol. 2010 Jun;22(6):515-25. doi: 10.1093/intimm/dxq036. Epub 2010 May 23. Int Immunol. 2010. PMID: 20497959

5

Fingolimod (FTY720), sphingosine 1-phosphate receptor modulator, shows superior efficacy as compared with interferon-β in mouse experimental autoimmune encephalomyelitis.

Chiba K, Kataoka H, Seki N, Shimano K, Koyama M, Fukunari A, Sugahara K, Sugita T. Chiba K, et al. Among authors: sugahara k. Int Immunopharmacol. 2011 Mar;11(3):366-72. doi: 10.1016/j.intimp.2010.10.005. Epub 2010 Oct 16. Int Immunopharmacol. 2011. PMID: 20955831

6

A phenotypic drug discovery study on thienodiazepine derivatives as inhibitors of T cell proliferation induced by CD28 co-stimulation leads to the discovery of a first bromodomain inhibitor.

Endo J, Hikawa H, Hamada M, Ishibuchi S, Fujie N, Sugiyama N, Tanaka M, Kobayashi H, Sugahara K, Oshita K, Iwata K, Ooike S, Murata M, Sumichika H, Chiba K, Adachi K. Endo J, et al. Among authors: sugahara k. Bioorg Med Chem Lett. 2016 Mar 1;26(5):1365-70. doi: 10.1016/j.bmcl.2016.01.084. Epub 2016 Feb 2. Bioorg Med Chem Lett. 2016. PMID: 26869194

7

Amiselimod (MT-1303), a novel sphingosine 1-phosphate receptor-1 functional antagonist, inhibits progress of chronic colitis induced by transfer of CD4+CD45RBhigh T cells.

Shimano K, Maeda Y, Kataoka H, Murase M, Mochizuki S, Utsumi H, Oshita K, Sugahara K. Shimano K, et al. Among authors: sugahara k. PLoS One. 2019 Dec 5;14(12):e0226154. doi: 10.1371/journal.pone.0226154. eCollection 2019. PLoS One. 2019. PMID: 31805144 Free PMC article.

8

Amiselimod (MT-1303), a Novel Sphingosine 1-Phosphate Receptor-1 Modulator, Potently Inhibits the Progression of Lupus Nephritis in Two Murine SLE Models.

Sugahara K, Maeda Y, Shimano K, Murase M, Mochiduki S, Takemoto K, Kakimoto T, Utsumi H, Oshita K, Kataoka H. Sugahara K, et al. J Immunol Res. 2019 Dec 23;2019:5821589. doi: 10.1155/2019/5821589. eCollection 2019. J Immunol Res. 2019. PMID: 31930150 Free PMC article.

9

Migration of CD4 T cells and dendritic cells toward sphingosine 1-phosphate (S1P) is mediated by different receptor subtypes: S1P regulates the functions of murine mature dendritic cells via S1P receptor type 3.

Maeda Y, Matsuyuki H, Shimano K, Kataoka H, Sugahara K, Chiba K. Maeda Y, et al. Among authors: sugahara k. J Immunol. 2007 Mar 15;178(6):3437-46. doi: 10.4049/jimmunol.178.6.3437. J Immunol. 2007. PMID: 17339438

10

Role of interferons (IFNs) in the differentiation of T peripheral helper (Tph) cells.

Tanemura S, Tsujimoto H, Seki N, Kojima S, Miyoshi F, Sugahara K, Yoshimoto K, Suzuki K, Kaneko Y, Chiba K, Takeuchi T. Tanemura S, et al. Among authors: sugahara k. Int Immunol. 2022 Sep 9;34(10):519-532. doi: 10.1093/intimm/dxac026. Int Immunol. 2022. PMID: 35723683

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