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In vitro selection of macrocyclic peptide inhibitors containing cyclic γ2,4-amino acids targeting the SARS-CoV-2 main protease.
Miura T, Malla TR, Owen CD, Tumber A, Brewitz L, McDonough MA, Salah E, Terasaka N, Katoh T, Lukacik P, Strain-Damerell C, Mikolajek H, Walsh MA, Kawamura A, Schofield CJ, Suga H. Miura T, et al. Among authors: suga h. Nat Chem. 2023 Jul;15(7):998-1005. doi: 10.1038/s41557-023-01205-1. Epub 2023 May 22. Nat Chem. 2023. PMID: 37217786 Free PMC article.
Flexizymes for genetic code reprogramming.
Goto Y, Katoh T, Suga H. Goto Y, et al. Among authors: suga h. Nat Protoc. 2011 Jun;6(6):779-90. doi: 10.1038/nprot.2011.331. Epub 2011 May 12. Nat Protoc. 2011. PMID: 21637198
Ribosomal synthesis of backbone macrocyclic peptides.
Katoh T, Goto Y, Reza MS, Suga H. Katoh T, et al. Among authors: suga h. Chem Commun (Camb). 2011 Sep 28;47(36):9946-58. doi: 10.1039/c1cc12647d. Epub 2011 Jul 15. Chem Commun (Camb). 2011. PMID: 21766105 Review.
The RNA origin of transfer RNA aminoacylation and beyond.
Suga H, Hayashi G, Terasaka N. Suga H, et al. Philos Trans R Soc Lond B Biol Sci. 2011 Oct 27;366(1580):2959-64. doi: 10.1098/rstb.2011.0137. Philos Trans R Soc Lond B Biol Sci. 2011. PMID: 21930588 Free PMC article.
Structural basis for the drug extrusion mechanism by a MATE multidrug transporter.
Tanaka Y, Hipolito CJ, Maturana AD, Ito K, Kuroda T, Higuchi T, Katoh T, Kato HE, Hattori M, Kumazaki K, Tsukazaki T, Ishitani R, Suga H, Nureki O. Tanaka Y, et al. Among authors: suga h. Nature. 2013 Apr 11;496(7444):247-51. doi: 10.1038/nature12014. Epub 2013 Mar 27. Nature. 2013. PMID: 23535598
Selection-based discovery of druglike macrocyclic peptides.
Passioura T, Katoh T, Goto Y, Suga H. Passioura T, et al. Among authors: suga h. Annu Rev Biochem. 2014;83:727-52. doi: 10.1146/annurev-biochem-060713-035456. Epub 2014 Feb 21. Annu Rev Biochem. 2014. PMID: 24580641 Review.
1,207 results