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In Search of Selectivity in Inhibition of ADAM10.
Mahasenan KV, Ding D, Gao M, Nguyen TT, Suckow MA, Schroeder VA, Wolter WR, Chang M, Mobashery S. Mahasenan KV, et al. Among authors: suckow ma. ACS Med Chem Lett. 2018 Jun 11;9(7):708-713. doi: 10.1021/acsmedchemlett.8b00163. eCollection 2018 Jul 12. ACS Med Chem Lett. 2018. PMID: 30034605 Free PMC article.
Structure-Activity Relationship for the 4(3H)-Quinazolinone Antibacterials.
Bouley R, Ding D, Peng Z, Bastian M, Lastochkin E, Song W, Suckow MA, Schroeder VA, Wolter WR, Mobashery S, Chang M. Bouley R, et al. Among authors: suckow ma. J Med Chem. 2016 May 26;59(10):5011-21. doi: 10.1021/acs.jmedchem.6b00372. Epub 2016 May 5. J Med Chem. 2016. PMID: 27088777 Free PMC article.
Exploitation of Conformational Dynamics in Imparting Selective Inhibition for Related Matrix Metalloproteinases.
Mahasenan KV, Bastian M, Gao M, Frost E, Ding D, Zorina-Lichtenwalter K, Jacobs J, Suckow MA, Schroeder VA, Wolter WR, Chang M, Mobashery S. Mahasenan KV, et al. Among authors: suckow ma. ACS Med Chem Lett. 2017 May 1;8(6):654-659. doi: 10.1021/acsmedchemlett.7b00130. eCollection 2017 Jun 8. ACS Med Chem Lett. 2017. PMID: 28626528 Free PMC article.
Validation of Matrix Metalloproteinase-9 (MMP-9) as a Novel Target for Treatment of Diabetic Foot Ulcers in Humans and Discovery of a Potent and Selective Small-Molecule MMP-9 Inhibitor That Accelerates Healing.
Nguyen TT, Ding D, Wolter WR, Pérez RL, Champion MM, Mahasenan KV, Hesek D, Lee M, Schroeder VA, Jones JI, Lastochkin E, Rose MK, Peterson CE, Suckow MA, Mobashery S, Chang M. Nguyen TT, et al. Among authors: suckow ma. J Med Chem. 2018 Oct 11;61(19):8825-8837. doi: 10.1021/acs.jmedchem.8b01005. Epub 2018 Sep 27. J Med Chem. 2018. PMID: 30212201
Structure-Activity Relationship for the Oxadiazole Class of Antibacterials.
Boudreau MA, Ding D, Meisel JE, Janardhanan J, Spink E, Peng Z, Qian Y, Yamaguchi T, Testero SA, O'Daniel PI, Leemans E, Lastochkin E, Song W, Schroeder VA, Wolter WR, Suckow MA, Mobashery S, Chang M. Boudreau MA, et al. Among authors: suckow ma. ACS Med Chem Lett. 2019 Oct 3;11(3):322-326. doi: 10.1021/acsmedchemlett.9b00379. eCollection 2020 Mar 12. ACS Med Chem Lett. 2019. PMID: 32184964 Free PMC article.
Selective water-soluble gelatinase inhibitor prodrugs.
Gooyit M, Lee M, Schroeder VA, Ikejiri M, Suckow MA, Mobashery S, Chang M. Gooyit M, et al. Among authors: suckow ma. J Med Chem. 2011 Oct 13;54(19):6676-90. doi: 10.1021/jm200566e. Epub 2011 Sep 6. J Med Chem. 2011. PMID: 21866961 Free PMC article.
130 results