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Discovery of antibiotic (E)-3-(3-carboxyphenyl)-2-(4-cyanostyryl)quinazolin-4(3H)-one.
Bouley R, Kumarasiri M, Peng Z, Otero LH, Song W, Suckow MA, Schroeder VA, Wolter WR, Lastochkin E, Antunes NT, Pi H, Vakulenko S, Hermoso JA, Chang M, Mobashery S. Bouley R, et al. Among authors: suckow ma. J Am Chem Soc. 2015 Feb 11;137(5):1738-41. doi: 10.1021/jacs.5b00056. Epub 2015 Feb 2. J Am Chem Soc. 2015. PMID: 25629446 Free PMC article.
Discovery of a new class of non-β-lactam inhibitors of penicillin-binding proteins with Gram-positive antibacterial activity.
O'Daniel PI, Peng Z, Pi H, Testero SA, Ding D, Spink E, Leemans E, Boudreau MA, Yamaguchi T, Schroeder VA, Wolter WR, Llarrull LI, Song W, Lastochkin E, Kumarasiri M, Antunes NT, Espahbodi M, Lichtenwalter K, Suckow MA, Vakulenko S, Mobashery S, Chang M. O'Daniel PI, et al. Among authors: suckow ma. J Am Chem Soc. 2014 Mar 5;136(9):3664-72. doi: 10.1021/ja500053x. Epub 2014 Feb 21. J Am Chem Soc. 2014. PMID: 24517363 Free PMC article.
Structure-activity relationship for the oxadiazole class of antibiotics.
Spink E, Ding D, Peng Z, Boudreau MA, Leemans E, Lastochkin E, Song W, Lichtenwalter K, O'Daniel PI, Testero SA, Pi H, Schroeder VA, Wolter WR, Antunes NT, Suckow MA, Vakulenko S, Chang M, Mobashery S. Spink E, et al. Among authors: suckow ma. J Med Chem. 2015 Feb 12;58(3):1380-9. doi: 10.1021/jm501661f. Epub 2015 Jan 30. J Med Chem. 2015. PMID: 25590813 Free PMC article.
Synergistic, collaterally sensitive β-lactam combinations suppress resistance in MRSA.
Gonzales PR, Pesesky MW, Bouley R, Ballard A, Biddy BA, Suckow MA, Wolter WR, Schroeder VA, Burnham CA, Mobashery S, Chang M, Dantas G. Gonzales PR, et al. Among authors: suckow ma. Nat Chem Biol. 2015 Nov;11(11):855-61. doi: 10.1038/nchembio.1911. Epub 2015 Sep 14. Nat Chem Biol. 2015. PMID: 26368589 Free PMC article.
Structure-Activity Relationship for the 4(3H)-Quinazolinone Antibacterials.
Bouley R, Ding D, Peng Z, Bastian M, Lastochkin E, Song W, Suckow MA, Schroeder VA, Wolter WR, Mobashery S, Chang M. Bouley R, et al. Among authors: suckow ma. J Med Chem. 2016 May 26;59(10):5011-21. doi: 10.1021/acs.jmedchem.6b00372. Epub 2016 May 5. J Med Chem. 2016. PMID: 27088777 Free PMC article.
A chemical biological strategy to facilitate diabetic wound healing.
Gooyit M, Peng Z, Wolter WR, Pi H, Ding D, Hesek D, Lee M, Boggess B, Champion MM, Suckow MA, Mobashery S, Chang M. Gooyit M, et al. Among authors: suckow ma. ACS Chem Biol. 2014 Jan 17;9(1):105-10. doi: 10.1021/cb4005468. Epub 2013 Sep 26. ACS Chem Biol. 2014. PMID: 24053680 Free PMC article.
Water-Soluble MMP-9 Inhibitor Reduces Lesion Volume after Severe Traumatic Brain Injury.
Lee M, Chen Z, Tomlinson BN, Gooyit M, Hesek D, Juárez MR, Nizam R, Boggess B, Lastochkin E, Schroeder VA, Wolter WR, Suckow MA, Cui J, Mobashery S, Gu Z, Chang M. Lee M, et al. Among authors: suckow ma. ACS Chem Neurosci. 2015 Oct 21;6(10):1658-64. doi: 10.1021/acschemneuro.5b00140. Epub 2015 Aug 14. ACS Chem Neurosci. 2015. PMID: 26241578 Free PMC article.
130 results