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Ceramide 1-phosphate is required for the translocation of group IVA cytosolic phospholipase A2 and prostaglandin synthesis.
Lamour NF, Subramanian P, Wijesinghe DS, Stahelin RV, Bonventre JV, Chalfant CE. Lamour NF, et al. Among authors: subramanian p. J Biol Chem. 2009 Sep 25;284(39):26897-907. doi: 10.1074/jbc.M109.001677. Epub 2009 Jul 23. J Biol Chem. 2009. PMID: 19632995 Free PMC article.
In opposition to this accepted mechanism of two decades, ceramide 1-phosphate (C1P) has been shown to increase the membrane association of cPLA(2)alpha in vitro via a novel site in the cationic beta-groove of the C2 domain (Stahelin, R. V., Subramanian, P., Vora, M. …
In opposition to this accepted mechanism of two decades, ceramide 1-phosphate (C1P) has been shown to increase the membrane association of c …
Ceramide 1-phosphate is a direct activator of cytosolic phospholipase A2.
Pettus BJ, Bielawska A, Subramanian P, Wijesinghe DS, Maceyka M, Leslie CC, Evans JH, Freiberg J, Roddy P, Hannun YA, Chalfant CE. Pettus BJ, et al. Among authors: subramanian p. J Biol Chem. 2004 Mar 19;279(12):11320-6. doi: 10.1074/jbc.M309262200. Epub 2003 Dec 15. J Biol Chem. 2004. PMID: 14676210 Free article.
Substrate specificity of human ceramide kinase.
Wijesinghe DS, Massiello A, Subramanian P, Szulc Z, Bielawska A, Chalfant CE. Wijesinghe DS, et al. Among authors: subramanian p. J Lipid Res. 2005 Dec;46(12):2706-16. doi: 10.1194/jlr.M500313-JLR200. Epub 2005 Sep 18. J Lipid Res. 2005. PMID: 16170208 Free article.
755 results