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Inhibition of myocardin-related transcription factor/serum response factor signaling decreases lung fibrosis and promotes mesenchymal cell apoptosis.
Sisson TH, Ajayi IO, Subbotina N, Dodi AE, Rodansky ES, Chibucos LN, Kim KK, Keshamouni VG, White ES, Zhou Y, Higgins PD, Larsen SD, Neubig RR, Horowitz JC. Sisson TH, et al. Am J Pathol. 2015 Apr;185(4):969-86. doi: 10.1016/j.ajpath.2014.12.005. Epub 2015 Feb 11. Am J Pathol. 2015. PMID: 25681733 Free PMC article.
Targeted injury of type II alveolar epithelial cells induces pulmonary fibrosis.
Sisson TH, Mendez M, Choi K, Subbotina N, Courey A, Cunningham A, Dave A, Engelhardt JF, Liu X, White ES, Thannickal VJ, Moore BB, Christensen PJ, Simon RH. Sisson TH, et al. Am J Respir Crit Care Med. 2010 Feb 1;181(3):254-63. doi: 10.1164/rccm.200810-1615OC. Epub 2009 Oct 22. Am J Respir Crit Care Med. 2010. PMID: 19850947 Free PMC article.
The vitronectin-binding function of PAI-1 exacerbates lung fibrosis in mice.
Courey AJ, Horowitz JC, Kim KK, Koh TJ, Novak ML, Subbotina N, Warnock M, Xue B, Cunningham AK, Lin Y, Goldklang MP, Simon RH, Lawrence DA, Sisson TH. Courey AJ, et al. Blood. 2011 Aug 25;118(8):2313-21. doi: 10.1182/blood-2010-12-324574. Epub 2011 Jul 6. Blood. 2011. PMID: 21734232 Free PMC article.
Urokinase Plasminogen Activator Overexpression Reverses Established Lung Fibrosis.
Horowitz JC, Tschumperlin DJ, Kim KK, Osterholzer JJ, Subbotina N, Ajayi IO, Teitz-Tennenbaum S, Virk A, Dotson M, Liu F, Sicard D, Jia S, Sisson TH. Horowitz JC, et al. Thromb Haemost. 2019 Dec;119(12):1968-1980. doi: 10.1055/s-0039-1697953. Epub 2019 Nov 8. Thromb Haemost. 2019. PMID: 31705517 Free PMC article.
19 results