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Loss of DP1 Aggravates Vascular Remodeling in Pulmonary Arterial Hypertension via mTORC1 Signaling.
He Y, Zuo C, Jia D, Bai P, Kong D, Chen D, Liu G, Li J, Wang Y, Chen G, Yan S, Xiao B, Zhang J, Piao L, Li Y, Deng Y, Li B, Roux PP, Andreasson KI, Breyer RM, Su Y, Wang J, Lyu A, Shen Y, Yu Y. He Y, et al. Among authors: su y. Am J Respir Crit Care Med. 2020 May 15;201(10):1263-1276. doi: 10.1164/rccm.201911-2137OC. Am J Respir Crit Care Med. 2020. PMID: 31917615 Free PMC article.
EP3 receptor deficiency attenuates pulmonary hypertension through suppression of Rho/TGF-β1 signaling.
Lu A, Zuo C, He Y, Chen G, Piao L, Zhang J, Xiao B, Shen Y, Tang J, Kong D, Alberti S, Chen D, Zuo S, Zhang Q, Yan S, Fei X, Yuan F, Zhou B, Duan S, Yu Y, Lazarus M, Su Y, Breyer RM, Funk CD, Yu Y. Lu A, et al. Among authors: su y. J Clin Invest. 2015 Mar 2;125(3):1228-42. doi: 10.1172/JCI77656. Epub 2015 Feb 9. J Clin Invest. 2015. PMID: 25664856 Free PMC article.
Galectin-3 Promotes Vascular Remodeling and Contributes to Pulmonary Hypertension.
Barman SA, Chen F, Li X, Haigh S, Stepp DW, Kondrikov D, Mahboubi K, Bordan Z, Traber P, Su Y, Fulton DJR. Barman SA, et al. Among authors: su y. Am J Respir Crit Care Med. 2018 Jun 1;197(11):1488-1492. doi: 10.1164/rccm.201711-2308LE. Am J Respir Crit Care Med. 2018. PMID: 29365276 Free PMC article. No abstract available.
Galectin-3 is expressed in vascular smooth muscle cells and promotes pulmonary hypertension through changes in proliferation, apoptosis, and fibrosis.
Barman SA, Li X, Haigh S, Kondrikov D, Mahboubi K, Bordan Z, Stepp DW, Zhou J, Wang Y, Weintraub DS, Traber P, Snider W, Jonigk D, Sullivan J, Crislip GR, Butcher JT, Thompson J, Su Y, Chen F, Fulton DJR. Barman SA, et al. Among authors: su y. Am J Physiol Lung Cell Mol Physiol. 2019 May 1;316(5):L784-L797. doi: 10.1152/ajplung.00186.2018. Epub 2019 Feb 6. Am J Physiol Lung Cell Mol Physiol. 2019. PMID: 30724100 Free PMC article.
Niacin Attenuates Pulmonary Hypertension Through H-PGDS in Macrophages.
Jia D, Bai P, Wan N, Liu J, Zhu Q, He Y, Chen G, Wang J, Chen H, Wang C, Lyu A, Lazarus M, Su Y, Urade Y, Yu Y, Zhang J, Shen Y. Jia D, et al. Among authors: su y. Circ Res. 2020 Oct 23;127(10):1323-1336. doi: 10.1161/CIRCRESAHA.120.316784. Epub 2020 Sep 11. Circ Res. 2020. PMID: 32912104
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