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Targeting Aggrephagy for the Treatment of Alzheimer's Disease.
Malampati S, Song JX, Chun-Kit Tong B, Nalluri A, Yang CB, Wang Z, Gopalkrishnashetty Sreenivasmurthy S, Zhu Z, Liu J, Su C, Krishnamoorthi S, Iyaswamy A, Cheung KH, Lu JH, Li AM. Malampati S, et al. Among authors: su c. Cells. 2020 Jan 28;9(2):311. doi: 10.3390/cells9020311. Cells. 2020. PMID: 32012902 Free PMC article. Review.
Lysosomal TPCN (two pore segment channel) inhibition ameliorates beta-amyloid pathology and mitigates memory impairment in Alzheimer disease.
Tong BC, Wu AJ, Huang AS, Dong R, Malampati S, Iyaswamy A, Krishnamoorthi S, Sreenivasmurthy SG, Zhu Z, Su C, Liu J, Song J, Lu JH, Tan J, Pan W, Li M, Cheung KH. Tong BC, et al. Among authors: su c. Autophagy. 2022 Mar;18(3):624-642. doi: 10.1080/15548627.2021.1945220. Epub 2021 Jul 27. Autophagy. 2022. PMID: 34313551 Free PMC article.
TFEB, a master regulator of autophagy and biogenesis, unexpectedly promotes apoptosis in response to the cyclopentenone prostaglandin 15d-PGJ2.
Yang CB, Liu J, Tong BC, Wang ZY, Zhu Z, Su CF, Sreenivasmurthy SG, Wu JX, Iyaswamy A, Krishnamoorthi S, Huang SY, Cheung KH, Song JX, Tan JQ, Lu JH, Li M. Yang CB, et al. Acta Pharmacol Sin. 2022 May;43(5):1251-1263. doi: 10.1038/s41401-021-00711-7. Epub 2021 Aug 20. Acta Pharmacol Sin. 2022. PMID: 34417577 Free PMC article.
8,193 results