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PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex.
Liu P, Gan W, Chin YR, Ogura K, Guo J, Zhang J, Wang B, Blenis J, Cantley LC, Toker A, Su B, Wei W. Liu P, et al. Among authors: su b. Cancer Discov. 2015 Nov;5(11):1194-209. doi: 10.1158/2159-8290.CD-15-0460. Epub 2015 Aug 20. Cancer Discov. 2015. PMID: 26293922 Free PMC article.
Mammalian TOR signaling to the AGC kinases.
Su B, Jacinto E. Su B, et al. Crit Rev Biochem Mol Biol. 2011 Dec;46(6):527-47. doi: 10.3109/10409238.2011.618113. Epub 2011 Oct 10. Crit Rev Biochem Mol Biol. 2011. PMID: 21981278 Free PMC article. Review.
Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis.
Liu P, Gan W, Inuzuka H, Lazorchak AS, Gao D, Arojo O, Liu D, Wan L, Zhai B, Yu Y, Yuan M, Kim BM, Shaik S, Menon S, Gygi SP, Lee TH, Asara JM, Manning BD, Blenis J, Su B, Wei W. Liu P, et al. Among authors: su b. Nat Cell Biol. 2013 Nov;15(11):1340-50. doi: 10.1038/ncb2860. Epub 2013 Oct 27. Nat Cell Biol. 2013. PMID: 24161930 Free PMC article.
Sin1/mTORC2 regulate B cell growth and metabolism by activating mTORC1 and Myc.
Li M, Lazorchak AS, Ouyang X, Zhang H, Liu H, Arojo OA, Yan L, Jin J, Han Y, Qu G, Fu Y, Xu X, Liu X, Zhang W, Yang Z, Ruan C, Wang Q, Liu D, Huang C, Lu L, Jiang S, Li F, Su B. Li M, et al. Among authors: su b. Cell Mol Immunol. 2019 Sep;16(9):757-769. doi: 10.1038/s41423-018-0185-x. Epub 2019 Jan 31. Cell Mol Immunol. 2019. PMID: 30705387 Free PMC article.
3,431 results