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The mammalian MAPK/ERK pathway exhibits properties of a negative feedback amplifier.
Sci Signal. 2010 Dec 21;3(153):ra90. doi: 10.1126/scisignal.2001212.
Sci Signal. 2010.
PMID: 21177493
Computational modelling of the receptor-tyrosine-kinase-activated MAPK pathway.
Orton RJ, Sturm OE, Vyshemirsky V, Calder M, Gilbert DR, Kolch W.
Orton RJ, et al. Among authors: sturm oe.
Biochem J. 2005 Dec 1;392(Pt 2):249-61. doi: 10.1042/BJ20050908.
Biochem J. 2005.
PMID: 16293107
Free PMC article.
Review.
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Computational modelling reveals feedback redundancy within the epidermal growth factor receptor/extracellular-signal regulated kinase signalling pathway.
Orton RJ, Sturm OE, Gormand A, Wolch W, Gilbert DR.
Orton RJ, et al. Among authors: sturm oe.
IET Syst Biol. 2008 Jul;2(4):173-83. doi: 10.1049/iet-syb:20070066.
IET Syst Biol. 2008.
PMID: 18681747
Free article.
Item in Clipboard
Computational modelling of cancerous mutations in the EGFR/ERK signalling pathway.
Orton RJ, Adriaens ME, Gormand A, Sturm OE, Kolch W, Gilbert DR.
Orton RJ, et al. Among authors: sturm oe.
BMC Syst Biol. 2009 Oct 5;3:100. doi: 10.1186/1752-0509-3-100.
BMC Syst Biol. 2009.
PMID: 19804630
Free PMC article.
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Apoptosis-Inducing-Factor-Dependent Mitochondrial Function Is Required for T Cell but Not B Cell Function.
Milasta S, Dillon CP, Sturm OE, Verbist KC, Brewer TL, Quarato G, Brown SA, Frase S, Janke LJ, Perry SS, Thomas PG, Green DR.
Milasta S, et al. Among authors: sturm oe.
Immunity. 2016 Jan 19;44(1):88-102. doi: 10.1016/j.immuni.2015.12.002. Epub 2016 Jan 12.
Immunity. 2016.
PMID: 26795252
Free PMC article.
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