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In vitro generation of mouse morula-like cells.
Li H, Chang L, Wu J, Huang J, Guan W, Bates LE, Stuart HT, Guo M, Zhang P, Huang B, Chen C, Zhang M, Chen J, Min M, Wu G, Hutchins AP, Silva JCR. Li H, et al. Among authors: stuart ht. Dev Cell. 2023 Nov 20;58(22):2510-2527.e7. doi: 10.1016/j.devcel.2023.09.013. Epub 2023 Oct 23. Dev Cell. 2023. PMID: 37875119
OCT4 induces embryonic pluripotency via STAT3 signaling and metabolic mechanisms.
Stirparo GG, Kurowski A, Yanagida A, Bates LE, Strawbridge SE, Hladkou S, Stuart HT, Boroviak TE, Silva JCR, Nichols J. Stirparo GG, et al. Among authors: stuart ht. Proc Natl Acad Sci U S A. 2021 Jan 19;118(3):e2008890118. doi: 10.1073/pnas.2008890118. Proc Natl Acad Sci U S A. 2021. PMID: 33452132 Free PMC article.
Sox2 modulation increases naïve pluripotency plasticity.
Tremble KC, Stirparo GG, Bates LE, Maskalenka K, Stuart HT, Jones K, Andersson-Rolf A, Radzisheuskaya A, Koo BK, Bertone P, Silva JCR. Tremble KC, et al. Among authors: stuart ht. iScience. 2021 Feb 6;24(3):102153. doi: 10.1016/j.isci.2021.102153. eCollection 2021 Mar 19. iScience. 2021. PMID: 33665571 Free PMC article.
Distinct Molecular Trajectories Converge to Induce Naive Pluripotency.
Stuart HT, Stirparo GG, Lohoff T, Bates LE, Kinoshita M, Lim CY, Sousa EJ, Maskalenka K, Radzisheuskaya A, Malcolm AA, Alves MRP, Lloyd RL, Nestorowa S, Humphreys P, Mansfield W, Reik W, Bertone P, Nichols J, Göttgens B, Silva JCR. Stuart HT, et al. Cell Stem Cell. 2019 Sep 5;25(3):388-406.e8. doi: 10.1016/j.stem.2019.07.009. Epub 2019 Aug 15. Cell Stem Cell. 2019. PMID: 31422912 Free PMC article.
StemBond hydrogels control the mechanical microenvironment for pluripotent stem cells.
Labouesse C, Tan BX, Agley CC, Hofer M, Winkel AK, Stirparo GG, Stuart HT, Verstreken CM, Mulas C, Mansfield W, Bertone P, Franze K, Silva JCR, Chalut KJ. Labouesse C, et al. Among authors: stuart ht. Nat Commun. 2021 Oct 21;12(1):6132. doi: 10.1038/s41467-021-26236-5. Nat Commun. 2021. PMID: 34675200 Free PMC article.
Dynamic transcriptional reprogramming leads to immunotherapeutic vulnerabilities in myeloma.
Frede J, Anand P, Sotudeh N, Pinto RA, Nair MS, Stuart H, Yee AJ, Vijaykumar T, Waldschmidt JM, Potdar S, Kloeber JA, Kokkalis A, Dimitrova V, Mann M, Laubach JP, Richardson PG, Anderson KC, Raje NS, Knoechel B, Lohr JG. Frede J, et al. Nat Cell Biol. 2021 Nov;23(11):1199-1211. doi: 10.1038/s41556-021-00766-y. Epub 2021 Oct 21. Nat Cell Biol. 2021. PMID: 34675390 Free PMC article.
3D ECM-rich environment sustains the identity of naive human iPSCs.
Cesare E, Urciuolo A, Stuart HT, Torchio E, Gesualdo A, Laterza C, Gagliano O, Martewicz S, Cui M, Manfredi A, Di Filippo L, Sabatelli P, Squarzoni S, Zorzan I, Betto RM, Martello G, Cacchiarelli D, Luni C, Elvassore N. Cesare E, et al. Among authors: stuart ht. Cell Stem Cell. 2022 Dec 1;29(12):1703-1717.e7. doi: 10.1016/j.stem.2022.11.011. Cell Stem Cell. 2022. PMID: 36459970 Free article.
12 results