Strushkevich N - Search Results

1

Transformations, NMR studies and biological testing of some 17β-isoxazolyl steroids and their heterocyclic ring cleavage derivatives.

Baranovsky A, Ladyko A, Shkel T, Sokolov S, Strushkevich N, Gilep A. Baranovsky A, et al. Among authors: strushkevich n. Steroids. 2021 Feb;166:108768. doi: 10.1016/j.steroids.2020.108768. Epub 2020 Nov 21. Steroids. 2021. PMID: 33232722

2

Compound I is the reactive intermediate in the first monooxygenation step during conversion of cholesterol to pregnenolone by cytochrome P450scc: EPR/ENDOR/cryoreduction/annealing studies.

Davydov R, Gilep AA, Strushkevich NV, Usanov SA, Hoffman BM. Davydov R, et al. J Am Chem Soc. 2012 Oct 17;134(41):17149-56. doi: 10.1021/ja3067226. Epub 2012 Oct 5. J Am Chem Soc. 2012. PMID: 23039857 Free PMC article.

3

Human steroid and oxysterol 7α-hydroxylase CYP7B1: substrate specificity, azole binding and misfolding of clinically relevant mutants.

Yantsevich AV, Dichenko YV, Mackenzie F, Mukha DV, Baranovsky AV, Gilep AA, Usanov SA, Strushkevich NV. Yantsevich AV, et al. FEBS J. 2014 Mar;281(6):1700-13. doi: 10.1111/febs.12733. Epub 2014 Feb 20. FEBS J. 2014. PMID: 24491228 Free article.

4

Evidence That Compound I Is the Active Species in Both the Hydroxylase and Lyase Steps by Which P450scc Converts Cholesterol to Pregnenolone: EPR/ENDOR/Cryoreduction/Annealing Studies.

Davydov R, Strushkevich N, Smil D, Yantsevich A, Gilep A, Usanov S, Hoffman BM. Davydov R, et al. Among authors: strushkevich n. Biochemistry. 2015 Dec 8;54(48):7089-97. doi: 10.1021/acs.biochem.5b00903. Epub 2015 Nov 25. Biochemistry. 2015. PMID: 26603348 Free PMC article.

5

Thermodynamics of interactions between mammalian cytochromes P450 and b5.

Yablokov E, Florinskaya A, Medvedev A, Sergeev G, Strushkevich N, Luschik A, Shkel T, Haidukevich I, Gilep A, Usanov S, Ivanov A. Yablokov E, et al. Among authors: strushkevich n. Arch Biochem Biophys. 2017 Apr 1;619:10-15. doi: 10.1016/j.abb.2017.02.006. Epub 2017 Feb 24. Arch Biochem Biophys. 2017. PMID: 28238672

6

New azole derivatives of [17(20)E]-21-norpregnene: Synthesis and inhibition of prostate carcinoma cell growth.

Dalidovich TS, Hurski AL, Morozevich GE, Latysheva AS, Sushko TA, Strushkevich NV, Gilep AA, Misharin AY, Zhabinskii VN, Khripach VA. Dalidovich TS, et al. Among authors: strushkevich nv. Steroids. 2019 Jul;147:10-18. doi: 10.1016/j.steroids.2018.08.004. Epub 2018 Aug 25. Steroids. 2019. PMID: 30149075

7

Assessment of electrocatalytic hydroxylase activity of cytochrome P450 3A4 (CYP3A4) by means of derivatization of 6β-hydroxycortisol by sulfuric acid for fluorimetric assay.

Kuzikov A, Masamrekh R, Shkel T, Strushkevich N, Gilep A, Usanov S, Archakov A, Shumyantseva V. Kuzikov A, et al. Among authors: strushkevich n. Talanta. 2019 May 1;196:231-236. doi: 10.1016/j.talanta.2018.12.041. Epub 2018 Dec 14. Talanta. 2019. PMID: 30683357

8

A large-scale comparative analysis of affinity, thermodynamics and functional characteristics of interactions of twelve cytochrome P450 isoforms and their redox partners.

Yablokov EO, Sushko TA, Ershov PV, Florinskaya AV, Gnedenko OV, Shkel TV, Grabovec IP, Strushkevich NV, Kaluzhskiy LA, Usanov SA, Gilep AA, Ivanov AS. Yablokov EO, et al. Biochimie. 2019 Jul;162:156-166. doi: 10.1016/j.biochi.2019.04.020. Epub 2019 Apr 26. Biochimie. 2019. PMID: 31034920

9

In vitro interactions of abiraterone, erythromycin, and CYP3A4: implications for drug-drug interactions.

Masamrekh RA, Kuzikov AV, Haurychenka YI, Shcherbakov KA, Veselovsky AV, Filimonov DA, Dmitriev AV, Zavialova MG, Gilep AA, Shkel TV, Strushkevich NV, Usanov SA, Archakov AI, Shumyantseva VV. Masamrekh RA, et al. Fundam Clin Pharmacol. 2020 Feb;34(1):120-130. doi: 10.1111/fcp.12497. Epub 2019 Aug 5. Fundam Clin Pharmacol. 2020. PMID: 31286572

10

Estimation of the inhibiting impact of abiraterone D4A metabolite on human steroid 21-monooxygenase (CYP21A2).

Masamrekh R, Filippova T, Haurychenka Y, Shcherbakov K, Veselovsky A, Strushkevich N, Shkel T, Gilep A, Usanov S, Shumyantseva V, Kuzikov A. Masamrekh R, et al. Among authors: strushkevich n. Steroids. 2020 Feb;154:108528. doi: 10.1016/j.steroids.2019.108528. Epub 2019 Oct 31. Steroids. 2020. PMID: 31678135

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