Strushkevich N - Search Results

1

Hydroxylation of Antitubercular Drug Candidate, SQ109, by Mycobacterial Cytochrome P450.

Bukhdruker S, Varaksa T, Grabovec I, Marin E, Shabunya P, Kadukova M, Grudinin S, Kavaleuski A, Gusach A, Gilep A, Borshchevskiy V, Strushkevich N. Bukhdruker S, et al. Among authors: strushkevich n. Int J Mol Sci. 2020 Oct 16;21(20):7683. doi: 10.3390/ijms21207683. Int J Mol Sci. 2020. PMID: 33081390 Free PMC article.

2

Structural basis for pregnenolone biosynthesis by the mitochondrial monooxygenase system.

Strushkevich N, MacKenzie F, Cherkesova T, Grabovec I, Usanov S, Park HW. Strushkevich N, et al. Proc Natl Acad Sci U S A. 2011 Jun 21;108(25):10139-43. doi: 10.1073/pnas.1019441108. Epub 2011 Jun 2. Proc Natl Acad Sci U S A. 2011. PMID: 21636783 Free PMC article.

3

Structural insights into aldosterone synthase substrate specificity and targeted inhibition.

Strushkevich N, Gilep AA, Shen L, Arrowsmith CH, Edwards AM, Usanov SA, Park HW. Strushkevich N, et al. Mol Endocrinol. 2013 Feb;27(2):315-24. doi: 10.1210/me.2012-1287. Epub 2013 Jan 15. Mol Endocrinol. 2013. PMID: 23322723 Free PMC article.

4

Human steroid and oxysterol 7α-hydroxylase CYP7B1: substrate specificity, azole binding and misfolding of clinically relevant mutants.

Yantsevich AV, Dichenko YV, Mackenzie F, Mukha DV, Baranovsky AV, Gilep AA, Usanov SA, Strushkevich NV. Yantsevich AV, et al. FEBS J. 2014 Mar;281(6):1700-13. doi: 10.1111/febs.12733. Epub 2014 Feb 20. FEBS J. 2014. PMID: 24491228 Free article.

5

Structural characterization of human cholesterol 7α-hydroxylase.

Tempel W, Grabovec I, MacKenzie F, Dichenko YV, Usanov SA, Gilep AA, Park HW, Strushkevich N. Tempel W, et al. Among authors: strushkevich n. J Lipid Res. 2014 Sep;55(9):1925-32. doi: 10.1194/jlr.M050765. Epub 2014 Jun 13. J Lipid Res. 2014. PMID: 24927729 Free PMC article.

6

Thermodynamics of interactions between mammalian cytochromes P450 and b5.

Yablokov E, Florinskaya A, Medvedev A, Sergeev G, Strushkevich N, Luschik A, Shkel T, Haidukevich I, Gilep A, Usanov S, Ivanov A. Yablokov E, et al. Among authors: strushkevich n. Arch Biochem Biophys. 2017 Apr 1;619:10-15. doi: 10.1016/j.abb.2017.02.006. Epub 2017 Feb 24. Arch Biochem Biophys. 2017. PMID: 28238672

7

New azole derivatives of [17(20)E]-21-norpregnene: Synthesis and inhibition of prostate carcinoma cell growth.

Dalidovich TS, Hurski AL, Morozevich GE, Latysheva AS, Sushko TA, Strushkevich NV, Gilep AA, Misharin AY, Zhabinskii VN, Khripach VA. Dalidovich TS, et al. Among authors: strushkevich nv. Steroids. 2019 Jul;147:10-18. doi: 10.1016/j.steroids.2018.08.004. Epub 2018 Aug 25. Steroids. 2019. PMID: 30149075

8

Assessment of electrocatalytic hydroxylase activity of cytochrome P450 3A4 (CYP3A4) by means of derivatization of 6β-hydroxycortisol by sulfuric acid for fluorimetric assay.

Kuzikov A, Masamrekh R, Shkel T, Strushkevich N, Gilep A, Usanov S, Archakov A, Shumyantseva V. Kuzikov A, et al. Among authors: strushkevich n. Talanta. 2019 May 1;196:231-236. doi: 10.1016/j.talanta.2018.12.041. Epub 2018 Dec 14. Talanta. 2019. PMID: 30683357

9

A large-scale comparative analysis of affinity, thermodynamics and functional characteristics of interactions of twelve cytochrome P450 isoforms and their redox partners.

Yablokov EO, Sushko TA, Ershov PV, Florinskaya AV, Gnedenko OV, Shkel TV, Grabovec IP, Strushkevich NV, Kaluzhskiy LA, Usanov SA, Gilep AA, Ivanov AS. Yablokov EO, et al. Biochimie. 2019 Jul;162:156-166. doi: 10.1016/j.biochi.2019.04.020. Epub 2019 Apr 26. Biochimie. 2019. PMID: 31034920

10

In vitro interactions of abiraterone, erythromycin, and CYP3A4: implications for drug-drug interactions.

Masamrekh RA, Kuzikov AV, Haurychenka YI, Shcherbakov KA, Veselovsky AV, Filimonov DA, Dmitriev AV, Zavialova MG, Gilep AA, Shkel TV, Strushkevich NV, Usanov SA, Archakov AI, Shumyantseva VV. Masamrekh RA, et al. Fundam Clin Pharmacol. 2020 Feb;34(1):120-130. doi: 10.1111/fcp.12497. Epub 2019 Aug 5. Fundam Clin Pharmacol. 2020. PMID: 31286572

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