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Pharmacological inhibition of MEK1/2 signaling disrupts bile acid metabolism through loss of Shp and enhanced Cyp7a1 expression.
Verzijl CRC, van de Peppel IP, Eilers RE, Bloks VW, Wolters JC, Koehorst M, Kloosterhuis NJ, Havinga R, Jalving M, Struik D, Jonker JW. Verzijl CRC, et al. Among authors: struik d. Biomed Pharmacother. 2023 Mar;159:114270. doi: 10.1016/j.biopha.2023.114270. Epub 2023 Jan 19. Biomed Pharmacother. 2023. PMID: 36680812 Free article.
Fibroblast Growth Factor Signaling in Metabolic Regulation.
Nies VJ, Sancar G, Liu W, van Zutphen T, Struik D, Yu RT, Atkins AR, Evans RM, Jonker JW, Downes MR. Nies VJ, et al. Among authors: struik d. Front Endocrinol (Lausanne). 2016 Jan 19;6:193. doi: 10.3389/fendo.2015.00193. eCollection 2015. Front Endocrinol (Lausanne). 2016. PMID: 26834701 Free PMC article. Review.
Effective treatment of steatosis and steatohepatitis by fibroblast growth factor 1 in mouse models of nonalcoholic fatty liver disease.
Liu W, Struik D, Nies VJ, Jurdzinski A, Harkema L, de Bruin A, Verkade HJ, Downes M, Evans RM, van Zutphen T, Jonker JW. Liu W, et al. Among authors: struik d. Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):2288-93. doi: 10.1073/pnas.1525093113. Epub 2016 Feb 8. Proc Natl Acad Sci U S A. 2016. PMID: 26858440 Free PMC article.
Dietary Sargassum fusiforme improves memory and reduces amyloid plaque load in an Alzheimer's disease mouse model.
Bogie J, Hoeks C, Schepers M, Tiane A, Cuypers A, Leijten F, Chintapakorn Y, Suttiyut T, Pornpakakul S, Struik D, Kerksiek A, Liu HB, Hellings N, Martinez-Martinez P, Jonker JW, Dewachter I, Sijbrands E, Walter J, Hendriks J, Groen A, Staels B, Lütjohann D, Vanmierlo T, Mulder M. Bogie J, et al. Among authors: struik d. Sci Rep. 2019 Mar 20;9(1):4908. doi: 10.1038/s41598-019-41399-4. Sci Rep. 2019. PMID: 30894635 Free PMC article.
Potential of therapeutic bile acids in the treatment of neonatal Hyperbilirubinemia.
van der Schoor LWE, Verkade HJ, Bertolini A, de Wit S, Mennillo E, Rettenmeier E, Weber AA, Havinga R, Valášková P, Jašprová J, Struik D, Bloks VW, Chen S, Schreuder AB, Vítek L, Tukey RH, Jonker JW. van der Schoor LWE, et al. Among authors: struik d. Sci Rep. 2021 May 27;11(1):11107. doi: 10.1038/s41598-021-90687-5. Sci Rep. 2021. PMID: 34045606 Free PMC article.
A novel role for GalNAc-T2 dependent glycosylation in energy homeostasis.
Verzijl CRC, Oldoni F, Loaiza N, Wolters JC, Rimbert A, Tian E, Yang W, Struik D, Smit M, Kloosterhuis NJ, Fernandez AJ, Samara NL, Ten Hagen KG, Dalal K, Chernish A, McCluggage P, Tabak LA, Jonker JW, Kuivenhoven JA. Verzijl CRC, et al. Among authors: struik d. Mol Metab. 2022 Jun;60:101472. doi: 10.1016/j.molmet.2022.101472. Epub 2022 Mar 15. Mol Metab. 2022. PMID: 35304331 Free PMC article.
Autocrine FGF1 signaling promotes glucose uptake in adipocytes.
Nies VJM, Struik D, Liu S, Liu W, Kruit JK, Downes M, van Zutphen T, Verkade HJ, Evans RM, Jonker JW. Nies VJM, et al. Among authors: struik d. Proc Natl Acad Sci U S A. 2022 Oct 4;119(40):e2122382119. doi: 10.1073/pnas.2122382119. Epub 2022 Sep 26. Proc Natl Acad Sci U S A. 2022. PMID: 36161959 Free PMC article.
20 results