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Chemoenzymatic Synthesis of ABC-Type Enantiostructured Triacylglycerols by the Use of the p-Methoxybenzyl Protective Group.
Haraldsdottir H, Gudmundsson HG, Linderborg KM, Yang B, Haraldsson GG. Haraldsdottir H, et al. Molecules. 2024 Apr 5;29(7):1633. doi: 10.3390/molecules29071633. Molecules. 2024. PMID: 38611912 Free PMC article.
This report demonstrates the first asymmetric synthesis of enantiopure structured triacylglycerols (TAGs) of the ABC type presenting three non-identical fatty acids, two of which are unsaturated. ...
This report demonstrates the first asymmetric synthesis of enantiopure structured triacylglycerols (TAGs) of the ABC type presenting …
Metabolomic Investigation of Brain and Liver in Rats Fed Docosahexaenoic Acid in Regio- and Enantiopure Triacylglycerols.
Pariyani R, Zhang Y, Haraldsson GG, Chen K, Linderborg KM, Yang B. Pariyani R, et al. Mol Nutr Food Res. 2024 Mar;68(5):e2300341. doi: 10.1002/mnfr.202300341. Epub 2024 Feb 23. Mol Nutr Food Res. 2024. PMID: 38396161
SCOPE: N-3 polyunsaturated fatty acids (n-3 PUFAs) play important roles in cognitive functions. However, there is a lack of knowledge on the metabolic impact of regio- and stereo-specific positioning of n-3 PUFAs in dietary triacylglycerols. METHODS AND RESULTS: Rats in a …
SCOPE: N-3 polyunsaturated fatty acids (n-3 PUFAs) play important roles in cognitive functions. However, there is a lack of knowledge …
Influence of Dietary Triacylglycerol Structure on the Accumulation of Docosahexaenoic Acid [22:6(n-3)] in Organs in a Short-Term Feeding Trial with Mildly Omega-3 Deficient Rats.
Kulkarni A, Linderborg KM, Zhao A, Kallio H, Haraldsson GG, Zhang Y, Yang B. Kulkarni A, et al. Mol Nutr Food Res. 2024 Mar;68(6):e2300635. doi: 10.1002/mnfr.202300635. Epub 2024 Feb 11. Mol Nutr Food Res. 2024. PMID: 38342587
METHODS AND RESULTS: In a 5-day feeding trial, mildly (n-3) deficient rats received 360 mg daily structured TAGs: sn-22:6(n-3)-18:0-18:0, sn-18:0-18:0-22:6(n-3), sn-18:0-22:6(n-3)-18:0, or tristearin. ...
METHODS AND RESULTS: In a 5-day feeding trial, mildly (n-3) deficient rats received 360 mg daily structured TAGs: sn-22:6(n-3)-18:0-1 …