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JAK-STAT signaling maintains homeostasis in T cells and macrophages.
Fortelny N, Farlik M, Fife V, Gorki AD, Lassnig C, Maurer B, Meissl K, Dolezal M, Boccuni L, Ravi Sundar Jose Geetha A, Akagha MJ, Karjalainen A, Shoebridge S, Farhat A, Mann U, Jain R, Tikoo S, Zila N, Esser-Skala W, Krausgruber T, Sitnik K, Penz T, Hladik A, Suske T, Zahalka S, Senekowitsch M, Barreca D, Halbritter F, Macho-Maschler S, Weninger W, Neubauer HA, Moriggl R, Knapp S, Sexl V, Strobl B, Decker T, Müller M, Bock C. Fortelny N, et al. Among authors: strobl b. Nat Immunol. 2024 Apr 24. doi: 10.1038/s41590-024-01804-1. Online ahead of print. Nat Immunol. 2024. PMID: 38658806
Editorial: Women in molecular innate immunity.
Granucci F, Marongiu L, Strobl B. Granucci F, et al. Among authors: strobl b. Front Immunol. 2023 Jul 11;14:1234710. doi: 10.3389/fimmu.2023.1234710. eCollection 2023. Front Immunol. 2023. PMID: 37497235 Free PMC article. No abstract available.
Duodenal macrophages control dietary iron absorption via local degradation of transferrin.
Sukhbaatar N, Schöller M, Fritsch SD, Linke M, Horer S, Träger M, Mazić M, Forisch S, Gonzales K, Kahler JP, Binder C, Lassnig C, Strobl B, Müller M, Scheiber-Mojdehkar B, Gundacker C, Dabsch S, Kain R, Hengstschläger M, Verhelst SHL, Weiss G, Theurl I, Weichhart T. Sukhbaatar N, et al. Among authors: strobl b. Blood. 2023 Jun 8;141(23):2878-2890. doi: 10.1182/blood.2022016632. Blood. 2023. PMID: 37018657 Free PMC article.
Tyk2 is a tumor suppressor in colorectal cancer.
Moritsch S, Mödl B, Scharf I, Janker L, Zwolanek D, Timelthaler G, Casanova E, Sibilia M, Mohr T, Kenner L, Herndler-Brandstetter D, Gerner C, Müller M, Strobl B, Eferl R. Moritsch S, et al. Among authors: strobl b. Oncoimmunology. 2022 Sep 26;11(1):2127271. doi: 10.1080/2162402X.2022.2127271. eCollection 2022. Oncoimmunology. 2022. PMID: 36185806 Free PMC article.
Trained immunity of alveolar macrophages requires metabolic rewiring and type 1 interferon signaling.
Zahalka S, Starkl P, Watzenboeck ML, Farhat A, Radhouani M, Deckert F, Hladik A, Lakovits K, Oberndorfer F, Lassnig C, Strobl B, Klavins K, Matsushita M, Sanin DE, Grzes KM, Pearce EJ, Gorki AD, Knapp S. Zahalka S, et al. Among authors: strobl b. Mucosal Immunol. 2022 May;15(5):896-907. doi: 10.1038/s41385-022-00528-5. Epub 2022 Jul 18. Mucosal Immunol. 2022. PMID: 35856089 Free PMC article.
Oncogenic TYK2 P760L kinase is effectively targeted by combinatorial TYK2, mTOR and CDK4/6 kinase blockade.
Woess K, Macho-Maschler S, Van Ingen Schenau DS, Butler M, Lassnig C, Valcanover D, Poelzl A, Meissl K, Maurer B, Brandstoetter T, Vogl C, Koren A, Kubicek S, Orlova A, Moriggl R, Strobl B, Sexl V, Van Leeuwen FN, Kuiper RP, Mueller M. Woess K, et al. Among authors: strobl b. Haematologica. 2023 Apr 1;108(4):993-1005. doi: 10.3324/haematol.2021.279848. Haematologica. 2023. PMID: 35021603 Free PMC article.
Single-cell transcriptional profiling of splenic fibroblasts reveals subset-specific innate immune signatures in homeostasis and during viral infection.
Pezoldt J, Wiechers C, Erhard F, Rand U, Bulat T, Beckstette M, Brendolan A, Huehn J, Kalinke U, Mueller M, Strobl B, Deplancke B, Čičin-Šain L, Sitnik KM. Pezoldt J, et al. Among authors: strobl b. Commun Biol. 2021 Dec 2;4(1):1355. doi: 10.1038/s42003-021-02882-9. Commun Biol. 2021. PMID: 34857864 Free PMC article.
Sustained Post-Developmental T-Bet Expression Is Critical for the Maintenance of Type One Innate Lymphoid Cells In Vivo.
Schroeder JH, Roberts LB, Meissl K, Lo JW, Hromadová D, Hayes K, Zabinski T, Read E, Moreira Heliodoro C, Reis R, Howard JK, Grencis RK, Neves JF, Strobl B, Lord GM. Schroeder JH, et al. Among authors: strobl b. Front Immunol. 2021 Oct 29;12:760198. doi: 10.3389/fimmu.2021.760198. eCollection 2021. Front Immunol. 2021. PMID: 34795671 Free PMC article.
Lactate and IL6 define separable paths of inflammatory metabolic adaptation.
Dichtl S, Lindenthal L, Zeitler L, Behnke K, Schlösser D, Strobl B, Scheller J, El Kasmi KC, Murray PJ. Dichtl S, et al. Among authors: strobl b. Sci Adv. 2021 Jun 23;7(26):eabg3505. doi: 10.1126/sciadv.abg3505. Print 2021 Jun. Sci Adv. 2021. PMID: 34162546 Free PMC article.
125 results