Strnad M - Search Results

1

Roscovitine sensitizes leukemia and lymphoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis.

Molinsky J, Klanova M, Koc M, Beranova L, Andera L, Ludvikova Z, Bohmova M, Gasova Z, Strnad M, Ivanek R, Trneny M, Necas E, Zivny J, Klener P. Molinsky J, et al. Among authors: strnad m. Leuk Lymphoma. 2013 Feb;54(2):372-80. doi: 10.3109/10428194.2012.710331. Epub 2012 Sep 8. Leuk Lymphoma. 2013. PMID: 22830613

2

Functional p53 in cells contributes to the anticancer effect of the cyclin-dependent kinase inhibitor roscovitine.

Paprskárová M, Krystof V, Jorda R, Dzubák P, Hajdúch M, Wesierska-Gadek J, Strnad M. Paprskárová M, et al. Among authors: strnad m. J Cell Biochem. 2009 Jun 1;107(3):428-37. doi: 10.1002/jcb.22139. J Cell Biochem. 2009. PMID: 19308936

3

3,5,7-Substituted Pyrazolo[4,3- d]pyrimidine Inhibitors of Cyclin-Dependent Kinases and Their Evaluation in Lymphoma Models.

Jorda R, Havlíček L, Šturc A, Tušková D, Daumová L, Alam M, Škerlová J, Nekardová M, Peřina M, Pospíšil T, Široká J, Urbánek L, Pachl P, Řezáčová P, Strnad M, Klener P, Kryštof V. Jorda R, et al. Among authors: strnad m. J Med Chem. 2019 May 9;62(9):4606-4623. doi: 10.1021/acs.jmedchem.9b00189. Epub 2019 Apr 17. J Med Chem. 2019. PMID: 30943029

4

3,5,7-Substituted Pyrazolo[4,3-d]Pyrimidine Inhibitors of Cyclin-Dependent Kinases and Cyclin K Degraders.

Jorda R, Havlíček L, Peřina M, Vojáčková V, Pospíšil T, Djukic S, Škerlová J, Grúz J, Renešová N, Klener P, Řezáčová P, Strnad M, Kryštof V. Jorda R, et al. Among authors: strnad m. J Med Chem. 2022 Jul 14;65(13):8881-8896. doi: 10.1021/acs.jmedchem.1c02184. Epub 2022 Jun 24. J Med Chem. 2022. PMID: 35749742

5

Cytokinin-derived cyclin-dependent kinase inhibitors: synthesis and cdc2 inhibitory activity of olomoucine and related compounds.

Havlícek L, Hanus J, Veselý J, Leclerc S, Meijer L, Shaw G, Strnad M. Havlícek L, et al. Among authors: strnad m. J Med Chem. 1997 Feb 14;40(4):408-12. doi: 10.1021/jm960666x. J Med Chem. 1997. PMID: 9046330

6

Potent induction of wild-type p53-dependent transcription in tumour cells by a synthetic inhibitor of cyclin-dependent kinases.

Kotala V, Uldrijan S, Horky M, Trbusek M, Strnad M, Vojtesek B. Kotala V, et al. Among authors: strnad m. Cell Mol Life Sci. 2001 Aug;58(9):1333-9. doi: 10.1007/PL00000944. Cell Mol Life Sci. 2001. PMID: 11577989

7

2,6,8,9-tetrasubstituted purines as new CDK1 inhibitors.

Moravec J, Krystof V, Hanus J, Havlícek L, Moravcová D, Fuksová K, Kuzma M, Lenobel R, Otyepka M, Strnad M. Moravec J, et al. Among authors: strnad m. Bioorg Med Chem Lett. 2003 Sep 15;13(18):2993-6. doi: 10.1016/s0960-894x(03)00632-2. Bioorg Med Chem Lett. 2003. PMID: 12941319

8

8-Azapurines as new inhibitors of cyclin-dependent kinases.

Havlicek L, Fuksova K, Krystof V, Orsag M, Vojtesek B, Strnad M. Havlicek L, et al. Among authors: strnad m. Bioorg Med Chem. 2005 Sep 15;13(18):5399-407. doi: 10.1016/j.bmc.2005.06.007. Bioorg Med Chem. 2005. PMID: 15993080

9

Pyrazolo[4,3-d]pyrimidine bioisostere of roscovitine: evaluation of a novel selective inhibitor of cyclin-dependent kinases with antiproliferative activity.

Jorda R, Havlícek L, McNae IW, Walkinshaw MD, Voller J, Sturc A, Navrátilová J, Kuzma M, Mistrík M, Bártek J, Strnad M, Krystof V. Jorda R, et al. Among authors: strnad m. J Med Chem. 2011 Apr 28;54(8):2980-93. doi: 10.1021/jm200064p. Epub 2011 Apr 6. J Med Chem. 2011. PMID: 21417417

10

Synthesis and in vitro biological evaluation of 2,6,9-trisubstituted purines targeting multiple cyclin-dependent kinases.

Zatloukal M, Jorda R, Gucký T, Řezníčková E, Voller J, Pospíšil T, Malínková V, Adamcová H, Kryštof V, Strnad M. Zatloukal M, et al. Among authors: strnad m. Eur J Med Chem. 2013 Mar;61:61-72. doi: 10.1016/j.ejmech.2012.06.036. Epub 2012 Jun 23. Eur J Med Chem. 2013. PMID: 22770608

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