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Reducing Akt2 in retinal pigment epithelial cells causes a compensatory increase in Akt1 and attenuates diabetic retinopathy.
Nat Commun. 2022 Oct 13;13(1):6045. doi: 10.1038/s41467-022-33773-0.
Nat Commun. 2022.
PMID: 36229454
Free PMC article.
βA3/A1-crystallin regulates apical polarity and EGFR endocytosis in retinal pigmented epithelial cells.
Shang P, Stepicheva N, Teel K, McCauley A, Fitting CS, Hose S, Grebe R, Yazdankhah M, Ghosh S, Liu H, Strizhakova A, Weiss J, Bhutto IA, Lutty GA, Jayagopal A, Qian J, Sahel JA, Samuel Zigler J Jr, Handa JT, Sergeev Y, Rajala RVS, Watkins S, Sinha D.
Shang P, et al. Among authors: strizhakova a.
Commun Biol. 2021 Jul 8;4(1):850. doi: 10.1038/s42003-021-02386-6.
Commun Biol. 2021.
PMID: 34239035
Free PMC article.
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A Novel Method of Mouse RPE Explant Culture and Effective Introduction of Transgenes Using Adenoviral Transduction for In Vitro Studies in AMD.
Shang P, Stepicheva NA, Liu H, Chowdhury O, Franks J, Sun M, Hose S, Ghosh S, Yazdankhah M, Strizhakova A, Stolz DB, Zigler JS Jr, Sinha D.
Shang P, et al. Among authors: strizhakova a.
Int J Mol Sci. 2021 Nov 5;22(21):11979. doi: 10.3390/ijms222111979.
Int J Mol Sci. 2021.
PMID: 34769409
Free PMC article.
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Increased LCN2 (lipocalin 2) in the RPE decreases autophagy and activates inflammasome-ferroptosis processes in a mouse model of dry AMD.
Gupta U, Ghosh S, Wallace CT, Shang P, Xin Y, Nair AP, Yazdankhah M, Strizhakova A, Ross MA, Liu H, Hose S, Stepicheva NA, Chowdhury O, Nemani M, Maddipatla V, Grebe R, Das M, Lathrop KL, Sahel JA, Zigler JS Jr, Qian J, Ghosh A, Sergeev Y, Handa JT, St Croix CM, Sinha D.
Gupta U, et al. Among authors: strizhakova a.
Autophagy. 2023 Jan;19(1):92-111. doi: 10.1080/15548627.2022.2062887. Epub 2022 Apr 26.
Autophagy. 2023.
PMID: 35473441
Free PMC article.
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Activated cGAS/STING signaling elicits endothelial cell senescence in early diabetic retinopathy.
Liu H, Ghosh S, Vaidya T, Bammidi S, Huang C, Shang P, Nair AP, Chowdhury O, Stepicheva NA, Strizhakova A, Hose S, Mitrousis N, Gadde SG, Mb T, Strassburger P, Widmer G, Lad EM, Fort PE, Sahel JA, Zigler JS Jr, Sethu S, Westenskow PD, Proia AD, Sodhi A, Ghosh A, Feenstra D, Sinha D.
Liu H, et al. Among authors: strizhakova a.
JCI Insight. 2023 Jun 22;8(12):e168945. doi: 10.1172/jci.insight.168945.
JCI Insight. 2023.
PMID: 37345657
Free PMC article.
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Microglia-Neutrophil Interactions Drive Dry AMD-like Pathology in a Mouse Model.
Boyce M, Xin Y, Chowdhury O, Shang P, Liu H, Koontz V, Strizhakova A, Nemani M, Hose S, Zigler JS Jr, Campbell M, Sinha D, Handa JT, Kaarniranta K, Qian J, Ghosh S.
Boyce M, et al. Among authors: strizhakova a.
Cells. 2022 Nov 9;11(22):3535. doi: 10.3390/cells11223535.
Cells. 2022.
PMID: 36428965
Free PMC article.
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