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Status of acute systemic toxicity testing requirements and data uses by U.S. regulatory agencies.
Strickland J, Clippinger AJ, Brown J, Allen D, Jacobs A, Matheson J, Lowit A, Reinke EN, Johnson MS, Quinn MJ Jr, Mattie D, Fitzpatrick SC, Ahir S, Kleinstreuer N, Casey W. Strickland J, et al. Regul Toxicol Pharmacol. 2018 Apr;94:183-196. doi: 10.1016/j.yrtph.2018.01.022. Epub 2018 Feb 3. Regul Toxicol Pharmacol. 2018. PMID: 29408321 Free PMC article. Review.
A Curated Database of Rodent Uterotrophic Bioactivity.
Kleinstreuer NC, Ceger PC, Allen DG, Strickland J, Chang X, Hamm JT, Casey WM. Kleinstreuer NC, et al. Among authors: strickland j. Environ Health Perspect. 2016 May;124(5):556-62. doi: 10.1289/ehp.1510183. Epub 2015 Oct 2. Environ Health Perspect. 2016. PMID: 26431337 Free PMC article. Review.
CONCLUSIONS: This uterotrophic database provides a valuable resource for understanding in vivo outcome variability and for evaluating the performance of in vitro assays that measure estrogenic activity. CITATION: Kleinstreuer NC, Ceger PC, Allen DG, Strickland J, Ch …
CONCLUSIONS: This uterotrophic database provides a valuable resource for understanding in vivo outcome variability and for evaluating the pe …
Integrated decision strategies for skin sensitization hazard.
Strickland J, Zang Q, Kleinstreuer N, Paris M, Lehmann DM, Choksi N, Matheson J, Jacobs A, Lowit A, Allen D, Casey W. Strickland J, et al. J Appl Toxicol. 2016 Sep;36(9):1150-62. doi: 10.1002/jat.3281. Epub 2016 Feb 6. J Appl Toxicol. 2016. PMID: 26851134 Free PMC article.
Multivariate models for prediction of human skin sensitization hazard.
Strickland J, Zang Q, Paris M, Lehmann DM, Allen D, Choksi N, Matheson J, Jacobs A, Casey W, Kleinstreuer N. Strickland J, et al. J Appl Toxicol. 2017 Mar;37(3):347-360. doi: 10.1002/jat.3366. Epub 2016 Aug 2. J Appl Toxicol. 2017. PMID: 27480324 Free PMC article.
Alternative approaches for identifying acute systemic toxicity: Moving from research to regulatory testing.
Hamm J, Sullivan K, Clippinger AJ, Strickland J, Bell S, Bhhatarai B, Blaauboer B, Casey W, Dorman D, Forsby A, Garcia-Reyero N, Gehen S, Graepel R, Hotchkiss J, Lowit A, Matheson J, Reaves E, Scarano L, Sprankle C, Tunkel J, Wilson D, Xia M, Zhu H, Allen D. Hamm J, et al. Among authors: strickland j. Toxicol In Vitro. 2017 Jun;41:245-259. doi: 10.1016/j.tiv.2017.01.004. Epub 2017 Jan 6. Toxicol In Vitro. 2017. PMID: 28069485 Free PMC article. Review.
Prediction of skin sensitization potency using machine learning approaches.
Zang Q, Paris M, Lehmann DM, Bell S, Kleinstreuer N, Allen D, Matheson J, Jacobs A, Casey W, Strickland J. Zang Q, et al. Among authors: strickland j. J Appl Toxicol. 2017 Jul;37(7):792-805. doi: 10.1002/jat.3424. Epub 2017 Jan 10. J Appl Toxicol. 2017. PMID: 28074598 Free PMC article.
667 results