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Discovery of a first-in-class EZH2 selective degrader.
Ma A, Stratikopoulos E, Park KS, Wei J, Martin TC, Yang X, Schwarz M, Leshchenko V, Rialdi A, Dale B, Lagana A, Guccione E, Parekh S, Parsons R, Jin J. Ma A, et al. Among authors: stratikopoulos e. Nat Chem Biol. 2020 Feb;16(2):214-222. doi: 10.1038/s41589-019-0421-4. Epub 2019 Dec 9. Nat Chem Biol. 2020. PMID: 31819273 Free PMC article.
AKT Degradation Selectively Inhibits the Growth of PI3K/PTEN Pathway-Mutant Cancers with Wild-Type KRAS and BRAF by Destabilizing Aurora Kinase B.
Xu J, Yu X, Martin TC, Bansal A, Cheung K, Lubin A, Stratikopoulos E, Cahuzac KM, Wang L, Xie L, Zhou R, Shen Y, Wu X, Yao S, Qiao R, Poulikakos PI, Chen X, Liu J, Jin J, Parsons R. Xu J, et al. Among authors: stratikopoulos e. Cancer Discov. 2021 Dec 1;11(12):3064-3089. doi: 10.1158/2159-8290.CD-20-0815. Cancer Discov. 2021. PMID: 34301793 Free PMC article.
PIK3CA and p53 Mutations Promote 4NQO-Initated Head and Neck Tumor Progression and Metastasis in Mice.
García-Carracedo D, Cai Y, Qiu W, Saeki K, Friedman RA, Lee A, Li Y, Goldberg EM, Stratikopoulos EE, Parsons R, Lu C, Efstratiadis A, Philipone EM, Yoon AJ, Su GH. García-Carracedo D, et al. Among authors: stratikopoulos ee. Mol Cancer Res. 2020 Jun;18(6):822-834. doi: 10.1158/1541-7786.MCR-19-0549. Epub 2020 Mar 9. Mol Cancer Res. 2020. PMID: 32152233 Free PMC article.
The hormonal action of IGF1 in postnatal mouse growth.
Stratikopoulos E, Szabolcs M, Dragatsis I, Klinakis A, Efstratiadis A. Stratikopoulos E, et al. Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19378-83. doi: 10.1073/pnas.0809223105. Epub 2008 Nov 25. Proc Natl Acad Sci U S A. 2008. PMID: 19033454 Free PMC article.
14 results