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The human anti-HIV antibodies 2F5, 2G12, and PG9 differ in their susceptibility to proteolytic degradation: down-regulation of endogenous serine and cysteine proteinase activities could improve antibody production in plant-based expression platforms.
Niemer M, Mehofer U, Torres Acosta JA, Verdianz M, Henkel T, Loos A, Strasser R, Maresch D, Rademacher T, Steinkellner H, Mach L. Niemer M, et al. Among authors: strasser r. Biotechnol J. 2014 Apr;9(4):493-500. doi: 10.1002/biot.201300207. Biotechnol J. 2014. PMID: 24478053 Free PMC article.
Functional Characterization of Pembrolizumab Produced in Nicotiana benthamiana Using a Rapid Transient Expression System.
Phakham T, Bulaon CJI, Khorattanakulchai N, Shanmugaraj B, Buranapraditkun S, Boonkrai C, Sooksai S, Hirankarn N, Abe Y, Strasser R, Rattanapisit K, Phoolcharoen W. Phakham T, et al. Among authors: strasser r. Front Plant Sci. 2021 Sep 9;12:736299. doi: 10.3389/fpls.2021.736299. eCollection 2021. Front Plant Sci. 2021. PMID: 34567049 Free PMC article.
Glycosylation of Plant-Produced Immunoglobulins.
Göritzer K, Strasser R. Göritzer K, et al. Among authors: strasser r. Exp Suppl. 2021;112:519-543. doi: 10.1007/978-3-030-76912-3_16. Exp Suppl. 2021. PMID: 34687021
751 results