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Gliotoxin from Aspergillus fumigatus Abrogates Leukotriene B4 Formation through Inhibition of Leukotriene A4 Hydrolase.
König S, Pace S, Pein H, Heinekamp T, Kramer J, Romp E, Straßburger M, Troisi F, Proschak A, Dworschak J, Scherlach K, Rossi A, Sautebin L, Haeggström JZ, Hertweck C, Brakhage AA, Gerstmeier J, Proschak E, Werz O. König S, et al. Among authors: strassburger m. Cell Chem Biol. 2019 Apr 18;26(4):524-534.e5. doi: 10.1016/j.chembiol.2019.01.001. Epub 2019 Feb 7. Cell Chem Biol. 2019. PMID: 30745237 Free article.
Transcriptome analysis of cyclic AMP-dependent protein kinase A-regulated genes reveals the production of the novel natural compound fumipyrrole by Aspergillus fumigatus.
Macheleidt J, Scherlach K, Neuwirth T, Schmidt-Heck W, Straßburger M, Spraker J, Baccile JA, Schroeder FC, Keller NP, Hertweck C, Heinekamp T, Brakhage AA. Macheleidt J, et al. Among authors: strassburger m. Mol Microbiol. 2015 Apr;96(1):148-62. doi: 10.1111/mmi.12926. Epub 2015 Mar 11. Mol Microbiol. 2015. PMID: 25582336 Free PMC article.
A Nonredundant Phosphopantetheinyl Transferase, PptA, Is a Novel Antifungal Target That Directs Secondary Metabolite, Siderophore, and Lysine Biosynthesis in Aspergillus fumigatus and Is Critical for Pathogenicity.
Johns A, Scharf DH, Gsaller F, Schmidt H, Heinekamp T, Straßburger M, Oliver JD, Birch M, Beckmann N, Dobb KS, Gilsenan J, Rash B, Bignell E, Brakhage AA, Bromley MJ. Johns A, et al. Among authors: strassburger m. mBio. 2017 Jul 18;8(4):e01504-16. doi: 10.1128/mBio.01504-16. mBio. 2017. PMID: 28720735 Free PMC article.
37 results