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Aryl Fluorosulfate Based Inhibitors That Covalently Target the SIRT5 Lysine Deacylase.
Bolding JE, Martín-Gago P, Rajabi N, Gamon LF, Hansen TN, Bartling CRO, Strømgaard K, Davies MJ, Olsen CA. Bolding JE, et al. Among authors: stromgaard k. Angew Chem Int Ed Engl. 2022 Nov 21;61(47):e202204565. doi: 10.1002/anie.202204565. Epub 2022 Oct 21. Angew Chem Int Ed Engl. 2022. PMID: 36130196 Free PMC article.
Small molecules from spiders used as chemical probes.
Olsen CA, Kristensen AS, Strømgaard K. Olsen CA, et al. Among authors: stromgaard k. Angew Chem Int Ed Engl. 2011 Nov 25;50(48):11296-311. doi: 10.1002/anie.201101599. Epub 2011 Oct 27. Angew Chem Int Ed Engl. 2011. PMID: 22034051 Review.
Probing Backbone Hydrogen Bonds in Proteins by Amide-to-Ester Mutations.
Sereikaitė V, Jensen TMT, Bartling CRO, Jemth P, Pless SA, Strømgaard K. Sereikaitė V, et al. Among authors: stromgaard k. Chembiochem. 2018 Oct 18;19(20):2136-2145. doi: 10.1002/cbic.201800350. Epub 2018 Oct 1. Chembiochem. 2018. PMID: 30073762 Review.
A high-affinity, bivalent PDZ domain inhibitor complexes PICK1 to alleviate neuropathic pain.
Christensen NR, De Luca M, Lever MB, Richner M, Hansen AB, Noes-Holt G, Jensen KL, Rathje M, Jensen DB, Erlendsson S, Bartling CR, Ammendrup-Johnsen I, Pedersen SE, Schönauer M, Nissen KB, Midtgaard SR, Teilum K, Arleth L, Sørensen AT, Bach A, Strømgaard K, Meehan CF, Vaegter CB, Gether U, Madsen KL. Christensen NR, et al. Among authors: stromgaard k. EMBO Mol Med. 2020 Jun 8;12(6):e11248. doi: 10.15252/emmm.201911248. Epub 2020 Apr 30. EMBO Mol Med. 2020. PMID: 32352640 Free PMC article.
Targeting the APP-Mint2 Protein-Protein Interaction with a Peptide-Based Inhibitor Reduces Amyloid-β Formation.
Bartling CRO, Jensen TMT, Henry SM, Colliander AL, Sereikaite V, Wenzler M, Jain P, Maric HM, Harpsøe K, Pedersen SW, Clemmensen LS, Haugaard-Kedström LM, Gloriam DE, Ho A, Strømgaard K. Bartling CRO, et al. Among authors: stromgaard k. J Am Chem Soc. 2021 Jan 20;143(2):891-901. doi: 10.1021/jacs.0c10696. Epub 2021 Jan 5. J Am Chem Soc. 2021. PMID: 33398998 Free PMC article.
152 results